Neonatal Thrombocytopenia and Platelet Transfusion - A UK Perspective

被引：27
|
作者：
Carr, Robert [1 ]
Kelly, Anne M. [2 ,3 ]
Williamson, Lorna M. [4 ]
机构：
[1] Kings Coll London, Guys & St Thomas Hosp, Dept Haematol, London SE1 9RT, England
[2] Univ Cambridge, Dept Haematol, Cambridge, England
[3] Univ Cambridge, Div Transfus Med, Cambridge, England
[4] NHS Blood & Transplant, Watford, England
来源：
NEONATOLOGY | 2015年 / 107卷 / 01期
关键词：
Infant; Newborn; Platelet transfusion; Thrombocytopenia; FETOMATERNAL ALLOIMMUNE THROMBOCYTOPENIA; RANDOMIZED CONTROLLED-TRIAL; INTENSIVE-CARE-UNIT; AUTOIMMUNE THROMBOCYTOPENIA; PREMATURE-INFANTS; MANAGEMENT; PRETERM; THROMBOPOIETIN; PROPHYLAXIS; MULTICENTER;
D O I：
10.1159/000365163
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Five percent of newborn infants admitted to UK neonatal units during a recent study developed a platelet count <60 x 10(9)/l, and 60% of these were transfused platelets. This review summarises the common causes and mechanisms of thrombocytopenia in the newborn. Relevant evidence relating the platelet count to the risk of haemorrhage is reviewed, and current UK guidance on transfusion thresholds outlined. The UK policy for the provision of platelets for transfusion to neonates is described, including the particular requirements for neonatal allo-immune thrombocytopenia. Finally, we look towards the future and prospects for reducing the need to expose newborns to donor-derived platelets. (C) 2014 S. Karger AG, Basel
引用
收藏
页码：1 / 7
页数：7
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