Transgenic mice with overexpression of syntaxin 4 have increased insulin sensitivity but mice with overexpression of Munc18c are insulin resistant in skeletal muscle

被引:0
|
作者
Park, SY
Spurlin, B
Kim, HJ
Higashimori, T
Choi, HJ
Kim, YJ
Noh, H
Thurmond, D
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:A282 / A282
页数:1
相关论文
共 50 条
  • [1] Skeletal muscle munc18c and syntaxin 4 in human obesity
    Bergman, Bryan C.
    Cornier, Marc-Andre
    Horton, Tracy J.
    Bessesen, Daniel H.
    Eckel, Robert H.
    NUTRITION & METABOLISM, 2008, 5 (1)
  • [2] Insulin resistance in tetracycline-repressible Munc18c transgenic mice
    Spurlin, BA
    Thomas, RM
    Nevins, AK
    Kim, HJ
    Kim, YJ
    Noh, HL
    Shulman, GI
    Kim, JK
    Thurmond, DC
    DIABETES, 2003, 52 (08) : 1910 - 1917
  • [3] Skeletal muscle munc18c and syntaxin 4 in human obesity
    Bryan C Bergman
    Marc-Andre Cornier
    Tracy J Horton
    Daniel H Bessesen
    Robert H Eckel
    Nutrition & Metabolism, 5
  • [4] Syntaxin 4 transgenic mice exhibit increased insulin sensitivity
    Spurlin, BA
    Nevins, AK
    Park, SY
    Kim, JK
    Thurmond, DC
    DIABETES, 2004, 53 : A15 - A15
  • [5] The role of syntaxin4 binding protein; Synip and Munc18c on insulin secretion
    Saito, T
    Okada, S
    Pessin, JE
    Ohshima, K
    Sato, M
    Mori, M
    DIABETES, 2000, 49 : A63 - A63
  • [6] Diabetes and liprotein lipase overexpression increase Munc18c gene expression in skeletal muscle: A potential mediator of free fatty acid induced insulin resistance
    Pulawa, L
    Schlaepfer, I
    Ferreira, L
    Eckel, R
    DIABETES, 2003, 52 : A319 - A319
  • [7] Phosphoenolpyruvate carboxykinase overexpression selectively attenuates insulin signaling and hepatic insulin sensitivity in transgenic mice
    Sun, Y
    Liu, S
    Ferguson, S
    Wang, LQ
    Klepcyk, P
    Yun, JS
    Friedman, JE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (26) : 23301 - 23307
  • [8] Transgenic mice with overexpression of syntaxin 4 are pqrotected from diet-induced insulin resistance in peripheral tissues
    Cho, YR
    Park, SY
    Spurlin, BA
    Kim, HJ
    Higashimori, T
    Kim, YJ
    Lee, M
    Thurmond, DC
    Kim, JK
    DIABETES, 2004, 53 : A71 - A72
  • [9] Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4
    Jewell, Jenna L.
    Oh, Eunjin
    Thurmond, Debbie C.
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2010, 298 (03) : R517 - R531
  • [10] Munc18c regulates insulin-stimulated GLUT4 translocation to the transverse tubules in skeletal muscle
    Khan, AH
    Thurmond, DC
    Yang, CM
    Ceresa, BP
    Sigmund, CD
    Pessin, JE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (06) : 4063 - 4069