Optimal control of epidemic spreading in the presence of social heterogeneity

被引:20
|
作者
Dimarco, G. [1 ]
Toscani, G. [2 ,3 ]
Zanella, M. [2 ]
机构
[1] Univ Ferrara, Dept Math & Comp Sci, Ferrara, Italy
[2] Univ Pavia, Dept Math F Casorati, Pavia, Italy
[3] Inst Appl Math & Informat Technol IMATI, Via Ferrata 5-A, Pavia, Italy
关键词
kinetic theory; mathematical epidemiology; optimal control; non-pharmaceutical interventions; COVID-19; UNCERTAINTY; EQUATIONS; MODELS;
D O I
10.1098/rsta.2021.0160
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools. However, population-wide lockdowns are far from being optimal, carrying heavy economic consequences. Therefore, there is nowadays a strong interest in designing more efficient restrictions. In this work, starting from a recent kinetic-type model which takes into account the heterogeneity described by the social contact of individuals, we analyse the effects of introducing an optimal control strategy into the system, to limit selectively the mean number of contacts and reduce consequently the number of infected cases. Thanks to a data-driven approach, we show that this new mathematical model permits us to assess the effects of the social limitations. Finally, using the model introduced here and starting from the available data, we show the effectiveness of the proposed selective measures to dampen the epidemic trends.This article is part of the theme issue 'Kinetic exchange models of societies and economies'.
引用
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页数:16
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