Haematopoiesis in Zebrafish (Danio Rerio)

被引:6
|
作者
Stosik, Michal [1 ]
Tokarz-Deptula, Beata [2 ]
Deptula, Wieslaw [3 ]
机构
[1] Univ Zielona Gora, Inst Biol Sci, Fac Biol Sci, Zielona Gora, Poland
[2] Univ Szczecin, Inst Biol, Szczecin, Poland
[3] Nicolaus Copernicus Univ Torun, Inst Vet Med, Fac Biol & Vet Sci, Torun, Poland
来源
FRONTIERS IN IMMUNOLOGY | 2022年 / 13卷
关键词
haematopoietic stem cells; embryonic period haematopoiesis; post-embryonic haematopoiesis; haematopoietic niches; Danio rerio (zebrafish); STEM-CELLS; DEFINITIVE HEMATOPOIESIS; ADULT ZEBRAFISH; AORTIC ENDOTHELIUM; VASCULAR NICHE; PROGENITOR; BLOOD; REVEALS; DIFFERENTIATION; ROLES;
D O I
10.3389/fimmu.2022.902941
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Haematopoiesis in fish and mammals is a complex process, and many aspects regarding its model and the differentiation of haematopoietic stem cells (HSCs) still remain enigmatic despite advanced studies. The effects of microenvironmental factors or HSCs niche and signalling pathways on haematopoiesis are also unclear. This review presents Danio rerio as a model organism for studies on haematopoiesis in vertebrates and discusses the development of this process during the embryonic period and in adult fish. It describes the role of the microenvironment of the haematopoietic process in regulating the formation and function of HSCs/HSPCs (hematopoietic stem/progenitor cells) and highlights facts and research areas important for haematopoiesis in fish and mammals.
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页数:10
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