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New synthesis of 3-aryl substituted oxindoles.
被引:9
|作者:
Ly, TM
Laso, NM
Zard, SZ
[1
]
机构:
[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France
[2] Ecole Polytech, CNRS, Organ Synth Lab, F-91128 Palaiseau, France
来源:
关键词:
D O I:
10.1016/S0040-4020(98)00172-0
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
A variety of 3-aryl substituted oxindoles can be rapidly constructed by treatment of a suitable 2,2-dimethoxy arylacetanilide, with titanium tetrachloride or boron trifluoride etherate; the synthesis of the precursors hinges on a powerful reaction between arylacetic acids and thionyl chloride. (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码:4889 / 4898
页数:10
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