PKC412 inhibits the ZNF198-FGFR1 fusion tyrosine kinase and is efficacious in treatment of t(8;13)(p11;q12) associated stem cell myeloproliferative disease.

被引:0
|
作者
Chen, J
DeAngelo, DJ
Kutok, JL
Williams, IR
Lee, BH
Wadleigh, M
Duclos, N
Cohen, S
Adelsperger, J
Okabe, R
Coburn, A
Galinsky, I
Huntly, BJP
Cohen, P
Meyer, T
Fabbro, D
Banerji, L
Griffin, JD
Xiao, S
Fletcher, JA
Stone, RM
Gilliland, DG
机构
[1] Harvard Univ, Sch Med, Howard Hughes Med Inst, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Boston, MA 02115 USA
[3] Brigham & Womens Hosp, Boston, MA 02115 USA
[4] Emory Univ, Atlanta, GA 30322 USA
[5] Novartis Pharma AG, Basel, Switzerland
关键词
D O I
10.1182/blood.V104.11.2549.2549
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
2549
引用
收藏
页码:698A / 698A
页数:1
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