Can SSRIs reduce the risk of preeclampsia in pregnant, depressed patients?

被引：3
|
作者：
Dawes, SD [1 ]
机构：
[1] Univ Calif Los Angeles, Dept Psychiat, Los Angeles Neuropsychiat Inst, Los Angeles, CA 90024 USA
来源：
MEDICAL HYPOTHESES | 2005年 / 64卷 / 01期
关键词：
D O I：
10.1016/j.mehy.2003.10.038
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Preeclampsia causes substantial morbidity and mortality. A significant part of the etiology of preeclampsia involves endothelial damage and platelet activation and in this way can be conceived as an illness with a pathophysiology similar to coronary artery disease. Depression is an independent risk factor for the progression of cardiovascular disease [Am Heart J 140 (2000) S57] and there is evidence to suggest that it may be a risk factor for preeclampsia as well. SSRIs have been shown to reduce the progression of coronary artery disease, independent of improvement in mood. SSRIs may also reduce risk factors for preeclampsia in addition to treating depression in pregnancy. This is an important area for further research. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：33 / 36
页数：4
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