Facile synthesis of 3,4-dihydroxyprolines as an application of the L-threonine aldolase-catalyzed aldol reaction

被引：0
|
作者：
Fujii, M [1 ]
Miura, T [1 ]
Kajimoto, T [1 ]
Ida, Y [1 ]
机构：
[1] Showa Univ, Sch Pharmaceut Sci, Shinagawa Ku, Tokyo 1428555, Japan
来源：
SYNLETT | 2000年 / 07期
关键词：
3,4-dihydroxyproline; L-threonine aldolase; aldol reactions; alpha-hydroxy-beta-L-amino acids; enzymes;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new facile synthesis of 3,4-dihydroxyprolines was attained by taking advantage of the L-threonine aldolase, which catalyzes the aldol condensation reaction of aldehydes with glycine affording beta-hydroxy-alpha-L-amino acids.
引用
收藏
页码：1046 / 1048
页数：3
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