Magneto-immunoassay of cancer biomarkers: Recent progress and challenges in biomedical analysis

被引：17

作者：

Kavetskyy, Taras ^{[1
,2
]}

Alipour, Mahdieh ^{[3
]}

Smutok, Oleh ^{[4
,5
]}

Mushynska, Oksana ^{[1
]}

Kiv, Arnold ^{[6
]}

Fink, Dietmar ^{[7
,8
]}

Farshchi, Fatemeh ^{[9
]}

Ahmadian, Elham ^{[9
]}

Hasanzadeh, Mohammad ^{[10
]}

机构：

[1] Drohobych Ivan Franko State Pedag Univ, Drogobych 82100, Ukraine

[2] John Paul II Catholic Univ Lublin, Lublin 20950, Poland

[3] Tabriz Univ Med Sci, Dent & Periodontal Res Ctr, Tabriz, Iran

[4] Clarkson Univ, Dept Chem & Biomol Sci, New York, NY 13699 USA

[5] Natl Acad Sci Ukraine, Inst Cell Biol, Lvov 79005, Ukraine

[6] South Ukrainian KD Ushynsky Natl Pedag Univ, Odessa 65020, Ukraine

[7] Univ Autonoma Metropolitana Iztapalapa, POB 55-534, Mexico City 09340, DF, Mexico

[8] ASCR, Inst Nucl Phys, Rez 25068, Czech Republic

[9] Tabriz Univ Med Sci, Pharmaceut Anal Res Ctr, Tabriz, Iran

[10] Tabriz Univ Med Sci, Kidney Res Ctr, Tabriz, Iran

来源：

MICROCHEMICAL JOURNAL | 2021年 / 167卷

基金：

新加坡国家研究基金会;

关键词：

Cancer; Nanobiomedicine; Biomedical analysis; Biotechnology; Magnetic nanomaterials; Electrochemistry; Optical biosensors; IRON-OXIDE NANOPARTICLES; ELECTROCHEMICAL IMMUNOSENSOR; LUNG-CANCER; ELECTROCHEMILUMINESCENCE IMMUNOSENSOR; CARCINOEMBRYONIC ANTIGEN; IMMUNOMAGNETIC DETECTION; GRAPHENE OXIDE; STRATEGIES; BIOSENSORS; SYSTEMS;

D O I：

10.1016/j.microc.2021.106320

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Ultrasensitive biomarker sensing has been used to develop novel strategies in detecting early stage cancer. Due to their unique characteristics, ie, ease of synthesis, conductivity and bio-compatibility, iron magnetic nanoparticles (MNPs) are exceptional nanomaterial in theragnostics. The current review focuses the critical role of iron MNPs in the development of several immunoassay technologies including electrochemical, electrochemiluminescent, photoelectrochemical, optical and microfluidic biosensors. Type and composition of magnetic particles, detection methods, relative specificity and sensitivity is discussed. Advantages and limitations of various strategies for label-free immunosensing of cancer biomarkers are explored.

引用

页数：13

共 50 条

[1] Dual-target magneto-immunoassay with bifunctional nanohybrids for breast cancer exosome detection
Haizan, Izzati
Choi, Min Yu
Park, Dong Hyeok
Choi, Jin-Ha
TALANTA, 2025, 286
[2] Recent Progress and Challenges in Nanotechnology for Biomedical Applications: An Insight into the Analysis of Neurotransmitters
Shankaran, Dhesingh Ravi
Miura, Norio
RECENT PATENTS ON NANOTECHNOLOGY, 2007, 1 (03) : 210 - 223
[3] Recent Progress in Challenges of Wireless Biomedical Sensor Network
Zhang, Lili
Wu, Xiaoming
2009 3RD INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING, VOLS 1-11, 2009, : 1211 - 1214
[4] Label-free electrochemical-immunoassay of cancer biomarkers: Recent progress and challenges in the efficient diagnosis of cancer employing electroanalysis and based on point of care (POC)
Hassanpour, Soodabeh
Hasanzadeh, Mohammad
MICROCHEMICAL JOURNAL, 2021, 168
[5] Recent progress and perspectives on prostate cancer biomarkers
Shingo Hatakeyama
Tohru Yoneyama
Yuki Tobisawa
Chikara Ohyama
International Journal of Clinical Oncology, 2017, 22 : 214 - 221
[6] Recent progress of chemotherapy and biomarkers for gastroesophageal cancer
Osamu Maeda
Yuichi Ando
World Journal of Gastrointestinal Oncology, 2019, (07) : 518 - 526
[7] Recent progress and perspectives on prostate cancer biomarkers
Hatakeyama, Shingo
Yoneyama, Tohru
Tobisawa, Yuki
Ohyama, Chikara
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2017, 22 (02) : 214 - 221
[8] Recent progress of chemotherapy and biomarkers for gastroesophageal cancer
Maeda, Osamu
Ando, Yuichi
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2019, 11 (07) : 518 - 526
[9] Quantum dots in biological and biomedical research: Recent progress and present challenges
Klostranec, Jesse M.
Chan, Warren C. W.
ADVANCED MATERIALS, 2006, 18 (15) : 1953 - 1964
[10] Biomedical applications of dendritic fibrous nanosilica (DFNS): recent progress and challenges
Shaban, Mina
Hasanzadeh, Mohammad
RSC ADVANCES, 2020, 10 (61) : 37116 - 37133

← 1 2 3 4 5 →