Transitions in morphological forms and rapid development of the asexual schizonts of Eimeria tenella through serial passaging in chicks

被引：2

作者：

Matsubayashi, Makoto ^{[1
,2
]}

Yamaguchi, Hiroki ^{[1
]}

Hatta, Takeshi ^{[3
]}

Kawahara, Fumiya ^{[4
]}

Hatabu, Toshimitsu ^{[5
]}

Iseki, Hiroshi ^{[6
]}

Yamagishi, Junya ^{[7
,8
]}

Isobe, Takashi ^{[9
]}

Teramoto, Isao ^{[2
]}

Kaneko, Akira ^{[2
,10
]}

Kita, Kiyoshi ^{[11
,12
]}

Tsuji, Naotoshi ^{[3
]}

Sasai, Kazumi ^{[1
]}

机构：

[1] Osaka Prefecture Univ, Grad Sch Life & Environm Sci, Dept Vet Sci, Izumisano, Osaka 5988531, Japan

[2] Osaka City Univ, Grad Sch Med, Dept Parasitol, Osaka, Osaka 5458585, Japan

[3] Kitasato Univ, Sch Med, Dept Parasitol, Minami Ku, Sagamihara, Kanagawa 2520374, Japan

[4] Mocky Poultry Practice, Tokyo 2050023, Japan

[5] Okayama Univ, Grad Sch Environm & Life Sci, Lab Anim Physiol, Okayama, Okayama 7008530, Japan

[6] Natl Agr & Food Res Org, Natl Inst Anim Hlth, Div Viral Dis & Epidemiol, Tsukuba, Ibaraki 3050856, Japan

[7] Hokkaido Univ, Res Ctr Zoonosis Control, Sapporo, Hokkaido 0010020, Japan

[8] Hokkaido Univ, GI CoRE, Global Stn Zoonosis Control, Sapporo, Hokkaido 0010020, Japan

[9] Japan Livestock Technol Assoc, Bunkyo Ku, Tokyo 1130034, Japan

[10] Osaka City Univ, Grad Sch Med, Res Ctr Infect Dis Sci, Osaka, Osaka 5458585, Japan

[11] Nagasaki Univ, Sch Trop Med & Global Hlth, Nagasaki, Nagasaki 8528523, Japan

[12] Nagasaki Univ, Inst Trop Med NEKKEN, Dept Host Def Biochem, Nagasaki, Nagasaki 8528523, Japan

来源：

INFECTION GENETICS AND EVOLUTION | 2019年 / 75卷

关键词：

Attenuation; Eimeria tenella; Schizont; Virulence; VIRULENT; STRAINS; STAGE;

D O I：

10.1016/j.meegid.2019.103993

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Attenuated strains of avian Eimeria parasites, generated by the selection of precocious lines through serial passaging in chicks, have been used widely as live vaccines. Detailed morphological transitions including their life cycle depending on the passages remain poorly understood. Here, we showed early development and acceleration of transitions in morphological forms of the asexual schizonts of E. tenella that had been attenuated for virulence by serial passaging. Our results may be helpful in understanding parasitism, facilitating further molecular analyses such as comparative genomic or transcriptomic tests.

引用

页数：4