Glucocorticoids Differentially Target SOCS1 and Type 1 Interferons to Regulate TLR-Induced STAT-1 Activation

被引：0
|
作者：
Bhattacharyya, Sandip [1 ]
Muglia, Louis [1 ]
机构：
[1] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA
来源：
BLOOD | 2009年 / 114卷 / 22期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：103 / 103
页数：1
相关论文
共 50 条
  • [1] Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation
    Bhattacharyya, Sandip
    Zhao, Yuxing
    Kay, Thomas W. H.
    Muglia, Louis J.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (23) : 9554 - 9559
  • [2] The molecular basis of JAK/STAT inhibition by SOCS1
    Nicholas P. D. Liau
    Artem Laktyushin
    Isabelle S. Lucet
    James M. Murphy
    Shenggen Yao
    Eden Whitlock
    Kimberley Callaghan
    Nicos A. Nicola
    Nadia J. Kershaw
    Jeffrey J. Babon
    [J]. Nature Communications, 9
  • [3] The molecular basis of JAK/STAT inhibition by SOCS1
    Liau, Nicholas P. D.
    Laktyushin, Artem
    Lucet, Isabelle S.
    Murphy, James M.
    Yao, Shenggen
    Whitlock, Eden
    Callaghan, Kimberley
    Nicola, Nicos A.
    Kershaw, Nadia J.
    Babon, Jeffrey J.
    [J]. NATURE COMMUNICATIONS, 2018, 9
  • [4] SOCS1 and SHP1 hypermethylation in multiple myeloma:: implications for epigenetic activation of the Jak/STAT pathway
    Chim, CS
    Fung, TK
    Cheung, WC
    Liang, R
    Kwong, YL
    [J]. BLOOD, 2004, 103 (12) : 4630 - 4635
  • [5] Activation of STAT1 & STAT4 by type 1 interferons: differential modulation by dexamethasone
    Fahey, AJ
    Robins, RA
    Constantinescu, CS
    [J]. IMMUNOLOGY, 2005, 116 : 103 - 103
  • [6] SOCS1/JAB is a negative regulator of LPS-induced macrophage activation
    Kinjyo, I
    Hanada, T
    Inagaki-Ohara, K
    Mori, H
    Aki, D
    Ohishi, M
    Yoshida, H
    Kubo, M
    Yoshimura, A
    [J]. IMMUNITY, 2002, 17 (05) : 583 - 591
  • [7] Acute alcohol induces SOCS3 and SOCS1 via STAT3 activation in human monocytes
    Norkina, Oxana
    Dolganiuc, Angela
    Kodys, Karen
    Mandrekar, Pranoti
    Szabo, Gyongyi
    [J]. JOURNAL OF IMMUNOLOGY, 2007, 178
  • [8] Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production
    Millrine, David
    Tei, Mami
    Gemechu, Yohannes
    Kishimoto, Tadamitsu
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (38) : 10625 - 10630
  • [9] SOCS1 and SHP1 hypermethylation in multiple myeloma: Potential implications for epigenetic activation of the Jak/STAT pathway.
    Chim, CS
    Kwong, YL
    Fung, TK
    Liang, R
    [J]. BLOOD, 2003, 102 (11) : 369B - 369B
  • [10] Downregulated SOCS1 expression activates the JAK1/STAT1 pathway and promotes polarization of macrophages into M1 type
    Liang, Yan-Bing
    Tang, Hao
    Chen, Zhi-Bin
    Zeng, Li-Jin
    Wu, Jing-Guo
    Yang, Wen
    Li, Zhen-Yu
    Ma, Zhong-Fu
    [J]. MOLECULAR MEDICINE REPORTS, 2017, 16 (05) : 6405 - 6411
12345