4-HYDROXY-2-QUINOLONES. 169. SYNTHESIS AND BROMINATION OF 1-ALLYL-3-(ARYLAMINOMETHYLENE)QUINOLINE-2,4-(1H,3H)-DIONES

被引：10
|
作者：
Ukrainets, I. V. [1 ]
Liu Yangyang [1 ]
Bereznyakova, N. L. [1 ]
Turov, A. V. [2 ]
机构：
[1] Natl Univ Pharm, UA-61002 Kharkov, Ukraine
[2] Taras Shevchenko Natl Univ, UA-01033 Kiev, Ukraine
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2009年 / 45卷 / 10期
关键词：
1-allyl-3-(arylaminomethylene)quinoline-2,4-(1H,3H)-diones; 1-allyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbaldehyde; enamines; oxazolo[3,2-a]quinolines; Schiff bases; bromination; halocyclization;
D O I：
10.1007/s10593-010-0412-6
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Bromination of 1-allyl-substituted 3-(arylaminomethylene)quinoline-2,4-(1H,3H)-diones with one equivalent of molecular bromine in glacial acetic acid and subsequent dilution of the reaction mixture with water is accompanied by halocyclization and hydrolysis to form 2-bromomethyl-5-oxo-1,2 dihydro-5H- oxazolo[3,2-a]quinoline-4-carbaldehyde.
引用
收藏
页码：1235 / 1240
页数：6
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