Tracking inorganic elements in GRMD blood dogs submitted to hASCs investigated by NAA technique

被引:1
|
作者
Metairon, S. [1 ]
Zamboni, C. B. [1 ]
Suzuki, M. F. [1 ]
Bueno, C. R., Jr. [2 ]
Andrade, T. O. [2 ]
Landini, V. [2 ]
Cangussu, E. B. [2 ]
Zatz, M. [2 ]
机构
[1] IPEN CNEN SP, Inst Pesquisas Energet & Nucl, Ctr Reator Pesquisa CRPq, Av Prof Lineu Prestes 2242, BR-05508000 Sao Paulo, SP, Brazil
[2] Univ Sao Paulo, Ctr Estudos Genoma Humano, Inst Biociencias, Rua Matao,Travessa 13,106, BR-05508090 Sao Paulo, SP, Brazil
关键词
Blood; NAA; Inorganic elements; Duchenne muscular dystrophy; hASCs treatment; Golden retriever; NEUTRON-ACTIVATION ANALYSIS; SKELETAL-MUSCLE; WHOLE-BLOOD; DYSTROPHIN;
D O I
10.1007/s10967-015-4394-9
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Investigation in blood of specific elements concentration are an important step in the development of new treatments. Recently, studies with human adipose derived from stromal cells injected systemic (medication that affects the entire body) into a golden retriever muscular dystrophy dogs shown to be able to express improvements in skeletal muscle. To check the alterations that this cell therapy may cause in the dogs, elements concentration in blood of treated dogs were investigated using NAA. These results were compared with the control and affected (untreated) dogs groups showing an improvement in Ca and Fe blood levels in treated dogs.
引用
收藏
页码:1645 / 1649
页数:5
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