Treatment of Familial Male-limited Precocious Puberty (Testotoxicosis) with Anastrozole and Bicalutamide in a Boy with a Novel Mutation in the Luteinizing Hormone Receptor

被引：4
|
作者：
Mitre, Naim [1 ]
Lteif, Aida [1 ]
机构：
[1] Mayo Clin, Coll Med, Div Pediat Endocrinol & Metab, Rochester, MN 55905 USA
来源：
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | 2009年 / 22卷 / 12期
关键词：
testotoxicosis; precocious puberty; endocrinology; genetics; GROWTH-HORMONE; SPIRONOLACTONE; TESTOLACTONE; DESLORELIN; ACETATE;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report the use of anastrozole and bicalutamide in a 5 year-old boy with familial male-limited precocious puberty. Clinical response showed decreased advancement of skeletal maturation, secondary sexual characteristics and aggressiveness with no short-term side effects. The combination seems a better option until long-term data are available.
引用
收藏
页码：1163 / 1167
页数：5
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