FACILE SYNTHESIS, SOLUBLIZATION STUDIES AND ANTI-INFLAMMATORY ACTIVITY OF AMORPHOUS ZINC(II) CENTERED ALDIMINE COMPLEXES

被引：4

作者：

Ali, Uzma ^{[1
]}

Maalik, Aneela ^{[2
]}

Taj, Muhammad Babar ^{[3
,4
]}

Raheel, Ahmad ^{[1
]}

Qureshi, Ahmad Kaleem ^{[4
]}

Imran, Muhammad ^{[3
]}

Sharif, Muhammad ^{[3
]}

Tirmizi, Syed Ahmad ^{[1
]}

Noor, Sadia ^{[5
]}

Alshater, Heba ^{[6
]}

机构：

[1] Quaid i Azam Univ, Dept Chem, Islamabad 44000, Pakistan

[2] Comsats Univ, Dept Chem, Pk Rd, Islamabad 44000, Pakistan

[3] Islamia Univ, Dept Chem, Bahawalpur 63100, Pakistan

[4] Univ Sahiwal, Dept Chem, Sahiwal 57000, Pakistan

[5] Univ Agr Faisalabad, Dept Chem, Faisalabad 38000, Pakistan

[6] Menoufia Univ, Dept Forens Med & Clin Toxicol, Menoufia 32871, Egypt

来源：

REVUE ROUMAINE DE CHIMIE | 2020年 / 65卷 / 10期

关键词：

SCHIFF-BASE COMPLEXES; METAL-COMPLEXES; SALICYLALDEHYDE; LUMINESCENCE; DOCKING;

D O I：

10.33224/rrch.2020.65.10.08

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this study, Zn(II) centered complexes with aldimine derivatives were synthesized using green solvent, polyethylene glycol (PEG-400) and amorphous complexes were characterized by FT-IR, multinuclear (H-1 and C-13 NMR), elemental and thermal analysis. Thermogravimetric analysis indicated the extended thermal stability of the synthesized complexes. All the Zn(II) complexes show very significant photoexcitation in the range of 318 - 384 nm and photoemission in the range of 502 - 562 nm. Among all the complexes, Zn(II) complex (3Zn) showed minimum band gap value, 2.35 eV. These amorphous complexes have been reported for their wide applications in biomedical sciences. The synthesized aldimine ligands and Zn(II) complexes were investigated for anti-inflammatory activity and these complexes showed more anti-inflammatory potential than the corresponding aldimine ligands. The solubilization of zinc complexes in sodium dodecyl sulphate was also investigated to reveal the interaction of metal complexes by using UV-Visible spectroscopy and electrical conductivity measurements.

引用

页码：929 / 941

页数：13

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