Ketamine Produces Structural Plasticity in Dopaminergic Neurons via Co-Activation of MEK-ERK and Akt-mTOR Pathways: Translation from Mouse Primary Culture to Human Ipsc-Derived Neurons

被引：0
|
作者：
Collo, Ginetta [1 ]
Cavalleri, Laura [1 ]
Bono, Federica [1 ]
Millan, Mark [1 ]
Chiamulera, Cristian [1 ]
Spano, Pierfranco [1 ]
Pich, Emilio Merlo [1 ]
机构：
[1] F Hoffmann La Roche, Basel, Switzerland
来源：
NEUROPSYCHOPHARMACOLOGY | 2014年 / 39卷
关键词：
dendrites; dopamine D3 receptors; AMPA antagonist; BDNF;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
T16
引用
收藏
页码：S300 / S300
页数：1
相关论文
共 8 条
  • [1] Testing the effect of dopamine agonists and of drugs of addiction on structural plasticity of dopaminergic neurons: translation from mouse primary cell culture to human iPSC-derived neurons
    Collo, G.
    Bono, F.
    Cavalleri, L.
    Spano, P. F.
    JOURNAL OF MOLECULAR NEUROSCIENCE, 2014, 53 : S30 - S30
  • [2] Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling
    L Cavalleri
    E Merlo Pich
    M J Millan
    C Chiamulera
    T Kunath
    P F Spano
    G Collo
    Molecular Psychiatry, 2018, 23 : 812 - 823
  • [3] Ketamine enhances structural plasticity in mouse mesencephalic and human iPSC-derived dopaminergic neurons via AMPAR-driven BDNF and mTOR signaling
    Cavalleri, L.
    Pich, E. Merlo
    Millan, M. J.
    Chiamulera, C.
    Kunath, T.
    Spano, P. F.
    Collo, G.
    MOLECULAR PSYCHIATRY, 2018, 23 (04) : 812 - 823
  • [4] Ketamine and pramipexole promote structural plasticity in human iPSC-derived dopaminergic neurons via D3 receptor and mTOR pathway
    Cavalleri, L.
    Pich, E. Merlo
    Chiamulera, C.
    Millan, M. J.
    Collo, G.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2017, 27 : S644 - S644
  • [5] Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling
    Collo, Ginetta
    Cavalleri, Laura
    Bono, Federica
    Mora, Cristina
    Fedele, Stefania
    Invernizzi, Roberto William
    Gennarelli, Massimo
    Piovani, Giovanna
    Kunath, Tilo
    Millan, Mark J.
    Pich, Emilio Merlo
    Spano, PierFranco
    NEURAL PLASTICITY, 2018, 2018
  • [6] Ketamine promotes plasticity in mouse-primary and human-iPSC-derived dopaminergic neurons via D3R and mTOR signalling
    Cavalleri, L.
    Chiamulera, C.
    Millan, M. J.
    Pich, E. Merlo
    Spano, P.
    Collo, G.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2016, 26 : S268 - S269
  • [7] Ketamine and Pramipexole Promote Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF/TrkB and mTOR Mediated Signalling: Possible Relevance for Treatment-Resistant Depression
    Pich, Emilio Merlo
    Collo, Ginetta
    Cavalleri, Laura
    Fedele, Stefania
    Chiamulera, Cristiano
    Millan, Mark J.
    Spano, PierFranco
    NEUROPSYCHOPHARMACOLOGY, 2016, 41 : S526 - S527
  • [8] Alpha6-Containing Nicotinic Acetylcholine Receptors Mediate Nicotine-Induced Structural Plasticity in Mouse and Human iPSC-Derived Dopaminergic Neurons
    Collo, Ginetta
    Cavalleri, Laura
    Zoli, Michele
    Maskos, Uwe
    Ratti, Emiliangelo
    Pich, Emilio Merlo
    FRONTIERS IN PHARMACOLOGY, 2018, 9
1