Evaluation of biocompatibility of fibroin-based electrospun nanofibrous mats for medical applications

被引：0
|
作者：
Safak, Serife [1 ]
Duzyer, Sebnem [1 ]
Karaca, Esra [1 ]
机构：
[1] Uludag Univ, Fac Engn, Dept Text Engn, Gorukle Campus, Bursa, Turkey
来源：
INDUSTRIA TEXTILA | 2016年 / 67卷 / 01期
关键词：
electrospinning; nanofiber; silk fibroin; biocompatibility; DRUG-DELIVERY; IN-VITRO; SILK; FIBROBLASTS; SCAFFOLDS; VIVO;
D O I：
暂无
中图分类号：
TB3 [工程材料学]; TS1 [纺织工业、染整工业];
学科分类号：
0805 ; 080502 ; 0821 ;
摘要：
In this study, Bombyx Mori silk fibroin and poly(vinyl alcohol) polymers were used. Blend solutions in two different ratios were prepared and solution parameters were determined by pH, conductivity and viscosity measurements. Silk fibroin/poly(vinyl alcohol) nanofibrous mats were produced by electrospinning process. The morphological characterization of electrospun nanofibers was examined by scanning electron microscope. Biocompatibility of the silk fibroin/poly(vinyl alcohol) nanofibrous mats was investigated by cytotoxicity, sensitization and irritation tests. As a result, both of the silk fibroin/poly(vinyl alcohol) nanofibrous mats were evaluated as noncytotoxic, nonirritative and sensitive materials.
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页码：3 / 9
页数：7
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