Biological therapy for the inner ear

被引：8
|
作者：
Patel, NP [1 ]
Mhatre, AN [1 ]
Lalwani, AK [1 ]
机构：
[1] NYU, Sch Med, Mendik Fdn Prof & Chairman, Lab Mol Otol,Dept Otolaryngol, New York, NY 10016 USA
来源：
EXPERT OPINION ON BIOLOGICAL THERAPY | 2004年 / 4卷 / 11期
关键词：
cochlear cellular therapy; cochlear gene therapy; stem cells; viral vectors;
D O I：
10.1517/14712598.4.11.1811
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Biological therapy for the inner ear has the potential to revolutionise the treatment of sensorineural hearing loss, the most common form of deafness. Progress in the molecular understanding of hearing and hearing loss, combined with advances in the fields of both gene and cellular therapy for the inner ear, is providing a robust foundation from which clinical translation is plausible. Potential areas of interest in gene therapy and its preclinical application to deafness are reviewed, and experimental progress that has occurred in cellular therapy for the inner ear is examined.
引用
收藏
页码：1811 / 1819
页数：9
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