IFITM3 regulates CMV-induced TLR-mediated inflammatory cytokine production by myeloid cells and restricts viral pathogenesis

被引:0
|
作者
Clement, M. [1 ]
Forbester, J. [1 ,2 ]
Wellington, D. [2 ]
Sabberwal, P. [1 ]
Marsden, M. [1 ]
Dougan, G. [3 ]
Dong, T. [2 ]
Humphreys, I. [1 ]
机构
[1] Cardiff Univ, Infect & Immun, Cardiff, S Glam, Wales
[2] Oxford Univ Hosp NHS Trust, Weatherall Inst Mol Med, Oxford, England
[3] Wellcome Trust Sanger Inst, Hinxton, England
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P1513
引用
收藏
页码:1054 / 1055
页数:2
相关论文
共 11 条
  • [1] IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses
    Clement, M.
    Forbester, J. L.
    Marsden, M.
    Sabberwal, P.
    Sommerville, M. S.
    Wellington, D.
    Dimonte, S.
    Clare, S.
    Harcourt, K.
    Yin, Z.
    Nobre, L.
    Antrobus, R.
    Jin, B.
    Chen, M.
    Makvandi-Nejad, S.
    Lindborg, J. A.
    Strittmatter, S. M.
    Weekes, M. P.
    Stanton, R. J.
    Dong, T.
    Humphreys, I. R.
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [2] IFITM3 restricts virus-induced inflammatory cytokine production by limiting Nogo-B mediated TLR responses
    M. Clement
    J. L. Forbester
    M. Marsden
    P. Sabberwal
    M. S. Sommerville
    D. Wellington
    S. Dimonte
    S. Clare
    K. Harcourt
    Z. Yin
    L. Nobre
    R. Antrobus
    B. Jin
    M. Chen
    S. Makvandi-Nejad
    J. A. Lindborg
    S. M. Strittmatter
    M. P. Weekes
    R. J. Stanton
    T. Dong
    I. R. Humphreys
    Nature Communications, 13
  • [3] IFITM3 restricts virus-induced pathogenesis by regulating myeloid cell production of interleukin-6
    Stacey, Maria A.
    Clare, Simon
    Marsden, Morgan
    Clement, Mathew
    Fielding, Ceri A.
    Johnson, Zoe
    Ferlin, Walter
    Jones, Simon A.
    Kellam, Paul
    Humphreys, Ian R.
    CYTOKINE, 2015, 76 (01) : 96 - 96
  • [4] The Role of JAK-3 in Regulating TLR-Mediated Inflammatory Cytokine Production in Innate Immune Cells
    Wang, Huizhi
    Brown, Jonathan
    Gao, Shegan
    Liang, Shuang
    Jotwani, Ravi
    Zhou, Huaxin
    Suttles, Jill
    Scott, David A.
    Lamont, Richard J.
    JOURNAL OF IMMUNOLOGY, 2013, 191 (03): : 1164 - 1174
  • [5] Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production
    Ko, Ryeojin
    Park, Jin Hee
    Ha, Hyunil
    Choi, Yongwon
    Lee, Soo Young
    NATURE COMMUNICATIONS, 2015, 6
  • [6] Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production
    Ryeojin Ko
    Jin Hee Park
    Hyunil Ha
    Yongwon Choi
    Soo Young Lee
    Nature Communications, 6
  • [7] TLR3 Priming Increases TLR4-and TLR6-Mediated Pro-Inflammatory Cytokine Production in Amniocytes, Myocytes and Vaginal Epithelial Cells.
    Rasheed, Zahirrah Begam Mohamed
    Rai, Ranjit Kaur
    Anucha, Eberechi
    Lee, Yun Soo
    Sung, Kim Hye
    MacIntyre, David Alan
    Bennett, Phillip Robert
    Sykes, Lynne
    REPRODUCTIVE SCIENCES, 2018, 25 : 258A - 258A
  • [8] Regulation of Viral Infection-induced Airway Remodeling Cytokine Production by the TLR3-EGFR Signaling Pathway in Human Bronchial Epithelial Cells
    Jiang, Jingjin
    Wang, Yuehong
    Tang, Xiaoping
    Yao, Yinan
    Zhou, Jianying
    COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2016, 13 (06) : 750 - 755
  • [9] Non-T cell activation linker (NTAL) negatively regulates TREM-1/DAP12-Induced inflammatory cytokine production in myeloid cells
    Tessarz, Anja S.
    Weiler, Sandra
    Zanzinger, Kai
    Angelisova, Pavla
    Horejsi, Vaclav
    Cerwenka, Adelheid
    JOURNAL OF IMMUNOLOGY, 2007, 178 (04): : 1991 - 1999
  • [10] TLR-Induced IL-12 and CCL2 Production by Myeloid Cells Is Dependent on Adenosine A3 Receptor-Mediated Signaling
    van der Putten, Celine
    Veth, Jennifer
    Sukurova, Lejla
    Zuiderwijk-Sick, Ella A.
    Simonetti, Elles
    Koenen, Hans J. P. M.
    Burm, Saskia M.
    van Noort, Johannes M.
    Ijzerman, Ad P.
    van Hijum, Sacha A. F. T.
    Diavatopoulos, Dimitri
    Bajramovic, Jeffrey J.
    JOURNAL OF IMMUNOLOGY, 2019, 202 (08): : 2421 - 2430