p110α and p110β increase production of not only D-3 but also D-4 position phosphorylated phosphoinositide in constitutively active and stimulation-dependent manners, respectively

被引:0
|
作者
Funaki, M
Katagiri, H
Anai, M
Nawano, M
Kikuchi, M
机构
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1300
引用
收藏
页码:A336 / A336
页数:1
相关论文
共 11 条
  • [1] p88/p110 type PI-kinase phosphorylates not only D-3 but also D-4 position of the inositol ring
    Funaki, M
    Katagiri, H
    Inukai, K
    Kikuchi, M
    Asano, T
    DIABETES, 1999, 48 : A74 - A74
  • [2] p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring
    Funaki, M
    Katagiri, H
    Kanda, A
    Anai, M
    Nawano, R
    Ogihara, T
    Inukai, K
    Fukushima, Y
    Ono, H
    Yazaki, Y
    Kikuchi, M
    Oka, Y
    Asano, T
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (31) : 22019 - 22024
  • [3] The roles of D-3 and D-4-phosphorylated phosphoinositides produced by p85/p110 type PI-kinase
    Funaki, M
    Katagiri, H
    Ono, H
    Kikuchi, M
    Asano, T
    MOLECULAR BIOLOGY OF THE CELL, 1999, 10 : 85A - 85A
  • [4] Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110α inhibitors
    Yiping Li
    Yawen Wang
    Fuqiang Zhang
    Journal of Molecular Modeling, 2010, 16 : 1449 - 1460
  • [5] Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110α inhibitors
    Li, Yiping
    Wang, Yawen
    Zhang, Fuqiang
    JOURNAL OF MOLECULAR MODELING, 2010, 16 (09) : 1449 - 1460
  • [6] Phosphoinositide-3-kinases (PI3Ks):: Combined comparative Modeling and 3D-QSAR to rationalize the inhibition of p110α
    Frederick, Raphael
    Denny, William A.
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2008, 48 (03) : 629 - 638
  • [7] Role of phosphoinositide 3-kinase p110δ in TLR4-and TLR9-mediated B cell cytokine production and differentiation
    Dil, Nyla
    Marshall, Aaron J.
    MOLECULAR IMMUNOLOGY, 2009, 46 (10) : 1970 - 1978
  • [8] Baculovirus production of fully-active phosphoinositide 3-kinase alpha as a p85α-p110α fusion for X-ray crystallographic analysis with ATP competitive enzyme inhibitors
    Sinnamon, Robert H.
    McDevitt, Patrick
    Pietrak, Beth L.
    Leydon, Vaughan R.
    Xue, Yu
    Lehr, Ruth
    Qi, Hongwei
    Burns, Matthew
    Elkins, Patricia
    Ward, Paris
    Vincentini, Giorgia
    Fisher, Donald
    Grimes, Maggie
    Brandt, Martin
    Auger, Kurt R.
    Ho, Thau
    Johanson, Kyung
    Jones, Christopher S.
    Schwartz, Benjamin
    Sweitzer, Thomas D.
    Kirkpatrick, Robert B.
    PROTEIN EXPRESSION AND PURIFICATION, 2010, 73 (02) : 167 - 176
  • [9] Synthesis and biological evaluation of pyrido[3′,2':4,5]furo [3,2-d]pyrimidine derivatives as novel PI3 kinase p110α inhibitors
    Hayakawa, Masahiko
    Kaizawa, Hiroyuki
    Moritomo, Hiroyuki
    Koizumi, Tomonobu
    Ohishi, Takahide
    Yamano, Mayumi
    Okada, Minoru
    Ohta, Mitsuaki
    Tsukamoto, Shin-ichi
    Raynaud, Florence I.
    Workman, Paul
    Waterfield, Michael D.
    Parker, Peter
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (09) : 2438 - 2442
  • [10] BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex
    Christian Hiepen
    Andreas Benn
    Agnieszka Denkis
    Ilya Lukonin
    Christoph Weise
    Jan H Boergermann
    Petra Knaus
    BMC Biology, 12