Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure (vol 160, e61141, 2020)

被引：0
|
作者：
Llewellyn, S. V.
机构：
来源：
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS | 2021年 / 167期
关键词：
D O I：
10.3791/6457
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页数：5
相关论文
共 17 条
  • [1] Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure
    Llewellyn, Samantha, V
    Conway, Gillian E.
    Shah, Ume-Kulsoom
    Evans, Stephen J.
    Jenkins, Gareth J. S.
    Clift, Martin J. D.
    Doak, Shareen H.
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2020, (160): : 1 - 10
  • [2] Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations (vol 35, pg 319, 2020)
    Conway, Gillian E.
    Shah, Ume-Kulsoom
    Llewellyn, Samantha
    Cervena, Tereza
    Evans, Stephen J.
    Al Ali, Abdullah S.
    Jenkins, Gareth J.
    Clift, Martin J. D.
    Doak, Shareen H.
    MUTAGENESIS, 2021, 36 (03) : 265 - 268
  • [3] Assessing the suitability of advanced 3D in vitro hepatic spheroid models as potential in vivo substitute models for acute and long-term engineered nanomaterial genotoxicity and hazard assessment.
    Llewellyn, S. V.
    Shah, U. -K.
    Evans, S. J.
    Jenkins, G. J.
    Clift, M. J.
    Doak, S. H.
    TOXICOLOGY LETTERS, 2019, 314 : S303 - S304
  • [4] Adaptation of the in vitro micronucleus assay for genotoxicity testing using 3D liver models supporting longer-term exposure durations
    Conway, Gillian E.
    Shah, Ume-Kulsoom
    Llewellyn, Samantha
    Cervena, Tereza
    Evans, Stephen J.
    Al Ali, Abdullah S.
    Jenkins, Gareth J.
    Clift, Martin J. D.
    Doak, Shareen H.
    MUTAGENESIS, 2020, 35 (04) : 319 - 329
  • [5] Multicellular 3D human liver microtissues for long-term toxicity testing
    Messner, Simon
    Walker, Paul
    Moritz, Wolfgang
    Kelm, Jens M.
    TOXICOLOGY LETTERS, 2013, 221 : S155 - S155
  • [6] Understanding the impact of more realistic low-dose, prolonged engineered nanomaterial exposure on genotoxicity using 3D models of the human liver
    Samantha V. Llewellyn
    Gillian E. Conway
    Ilaria Zanoni
    Amalie Kofoed Jørgensen
    Ume-Kulsoom Shah
    Didem Ag Seleci
    Johannes G. Keller
    Jeong Won Kim
    Wendel Wohlleben
    Keld Alstrup Jensen
    Anna Costa
    Gareth J. S. Jenkins
    Martin J. D. Clift
    Shareen H. Doak
    Journal of Nanobiotechnology, 19
  • [7] Understanding the impact of more realistic low-dose, prolonged engineered nanomaterial exposure on genotoxicity using 3D models of the human liver
    Llewellyn, Samantha V.
    Conway, Gillian E.
    Zanoni, Ilaria
    Jorgensen, Amalie Kofoed
    Shah, Ume-Kulsoom
    Seleci, Didem Ag
    Keller, Johannes G.
    Kim, Jeong Won
    Wohlleben, Wendel
    Jensen, Keld Alstrup
    Costa, Anna
    Jenkins, Gareth J. S.
    Clift, Martin J. D.
    Doak, Shareen H.
    JOURNAL OF NANOBIOTECHNOLOGY, 2021, 19 (01)
  • [8] A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis
    L. Smirnova
    G. Harris
    J. Delp
    M. Valadares
    D. Pamies
    H. T. Hogberg
    T. Waldmann
    M. Leist
    T. Hartung
    Archives of Toxicology, 2016, 90 : 2725 - 2743
  • [9] A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis
    Smirnova, L.
    Harris, G.
    Delp, J.
    Valadares, M.
    Pamies, D.
    Hogberg, H. T.
    Waldmann, T.
    Leist, M.
    Hartung, T.
    ARCHIVES OF TOXICOLOGY, 2016, 90 (11) : 2725 - 2743
  • [10] Human 3D Cultures as Models for Evaluating Magnetic Nanoparticle CNS Cytotoxicity after Short- and Repeated Long-Term Exposure
    De Simone, Uliana
    Roccio, Marianna
    Gribaldo, Laura
    Spinillo, Arsenio
    Caloni, Francesca
    Coccini, Teresa
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (07)
12