Heart failure with a preserved ejection fraction and the EMPEROR-Preserved Trial: a review of how we got here

被引:0
|
作者
de Abreu, Tiago Tribolet [1 ]
机构
[1] Hosp Espirito Santo Evora EPE, Serv Med, Evora, Portugal
关键词
Heart failure; Diastolic heart failure; Preserved ejection fraction; GUIDELINES; DIAGNOSIS; ECHOCARDIOGRAPHY; MANAGEMENT; COMMITTEE;
D O I
10.1007/s10741-022-10244-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure with a preserved ejection fraction (HFpEF), previously known as diastolic heart failure, was first recognized more than 50 years ago. In spite of all the advances in the knowledge of HFpEF, important questions remain, namely the fact that no therapy has been shown to improve outcomes in these patients. The EMPEROR-Preserved Trial, a trial on the use of empagliflozin on patients with HFpEF, published in October 2021, was the first trial to ever show a change in outcomes in these patients. This article reviews the history of HFpEF and the problems related to its definition and diagnosis over time, and critically reviews the results of the EMPEROR-Preserved Trial in light of these.
引用
收藏
页码:2077 / 2082
页数:6
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