Identification of novel small molecule CXCR4 inhibitors as anti-HIV agents

被引：0
|
作者：
Das, Debananda [1 ]
Maeda, Kenji [1 ]
Hayashi, Yasuhiro [1 ]
Gavande, Navnath [4 ,5 ]
Desai, Darshan V. [1 ]
Chang, Simon B. [1 ]
Ghosh, Arun K. [4 ,5 ]
Mitsuya, Hiroaki [1 ,2 ,3 ]
机构：
[1] NCI, Expt Retrovirol Sect, HIV & AIDS Malignancy Branch, NIH, Bethesda, MD 20892 USA
[2] Kumamoto Univ, Dept Hematol, Grad Sch Med & Pharmaceut Sci, Kumamoto, Japan
[3] Kumamoto Univ, Dept Infect Dis, Grad Sch Med & Pharmaceut Sci, Kumamoto, Japan
[4] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA
[5] Purdue Univ, Dept Med Chem, W Lafayette, IN 47907 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 248卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
406-COMP
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Small molecules anti-HIV therapeutics targeting CXCR4
    Grande, Fedora
    Garofalo, Antonio
    Neamati, Nouri
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2008, 14 (04) : 385 - 404
  • [2] Small Molecule Inhibitors of CXCR4
    Debnath, Bikash
    Xu, Shili
    Grande, Fedora
    Garofalo, Antonio
    Neamati, Nouri
    [J]. THERANOSTICS, 2013, 3 (01): : 47 - 75
  • [3] Novel N-substituted benzimidazole CXCR4 antagonists as potential anti-HIV agents
    Miller, John F.
    Turner, Elizabeth M.
    Gudmundsson, Kristjan S.
    Jenkinson, Stephen
    Spaltenstein, Andrew
    Thomson, Michael
    Wheelan, Pat
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (07) : 2125 - 2128
  • [4] Development of selective CXCR4 inhibitors with strong anti-HIV activity.
    Tamamura, H
    Hiramatsu, K
    Omagari, A
    Oishi, S
    Nakashima, H
    Peiper, SC
    Otaka, A
    Fujii, N
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 224 : U42 - U42
  • [5] Identification of CXCR4 inhibitors as a key therapeutic small molecule in renal fibrosis
    Kumar, Senthil G.
    Kishore, N.
    Elumalai, Elakkiya
    Gupta, Krishna Kant
    [J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 42 (16): : 8441 - 8453
  • [6] Anti-HIV Small-Molecule Binding in the Peptide Subpocket of the CXCR4:CVX15 Crystal Structure
    Cox, Bryan D.
    Prosser, Anthony R.
    Katzman, Brooke M.
    Alcaraz, Ana A.
    Liotta, Dennis C.
    Wilson, Lawrence J.
    Snyder, James P.
    [J]. CHEMBIOCHEM, 2014, 15 (11) : 1613 - 1619
  • [7] A specific CXCR4 antagonist with potent anti-HIV activity
    Hatse, S
    Princen, K
    Bridger, G
    Skerlj, R
    Henson, G
    De Clercq, E
    Schols, D
    [J]. ANTIVIRAL RESEARCH, 2002, 53 (03) : A36 - A36
  • [8] CXCR4 Is a Potential Target for Anti-HIV Gene Therapy
    Prokopovich, Appolinaria K.
    Litvinova, Irina S.
    Zubkova, Alexandra E.
    Yudkin, Dmitry V.
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (02)
  • [9] Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity
    Miller, John F.
    Gudmundsson, Kristjan S.
    Richardson, Leah D'Aurora
    Jenkinson, Stephen
    Spaltenstein, Andrew
    Thomson, Michael
    Wheelan, Pat
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (10) : 3026 - 3030
  • [10] Establishment of an Anti-HIV/AIDS Agents Screening Technique Based on Human CXCR4 Promoter
    Ma, Yunyun
    Feng, Long
    Li, Ming
    Wei, Yanping
    He, Tingyu
    Guo, Wentao
    Jin, Jing
    Dong, Ziming
    Zhao, Guoqiang
    [J]. LIFE SCIENCE JOURNAL-ACTA ZHENGZHOU UNIVERSITY OVERSEAS EDITION, 2010, 7 (02): : 1 - 7
12345