A simple pyrene-based fluorescent probe for highly selective detection of formaldehyde and its application in live-cell imaging

被引：43
|
作者：
Zhang, Di [1 ,2 ,3 ]
Liu, Dongmei [1 ,2 ,3 ]
Li, Man [1 ,2 ,3 ]
Yang, Yaqin [1 ,2 ,3 ]
Wang, Yun [1 ,2 ,3 ]
Yin, Haiyan [1 ,2 ,3 ]
Liu, Jihong [1 ,2 ,3 ]
Jia, Bin [1 ,2 ,3 ]
Wu, Xujin [1 ,2 ,3 ]
机构：
[1] Henan Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Zhengzhou 450002, Henan, Peoples R China
[2] Henan Key Lab Grain Qual & Safety & Testing, Zhengzhou 450002, Henan, Peoples R China
[3] Minist Agr, Lab Qual & Safety Risk Assessment Agroprod Zhengz, Zhengzhou 450002, Henan, Peoples R China
来源：
ANALYTICA CHIMICA ACTA | 2018年 / 1033卷
关键词：
Formaldehyde; Pyrene; Fluorescence; Probe; Turn-on; AQUEOUS-SOLUTION; ENDOGENOUS FORMALDEHYDE; SENSITIVE DETECTION; LIVING CELLS; ALDEHYDES;
D O I：
10.1016/j.aca.2018.05.065
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A novel and simple pyrene-based fluorescent probe (B1) was synthesized and used for the detection of formaldehyde (FA). When B1 was added to FA in CH3CH2OH/HEPES (10 mM, pH = 7.4, 1:99, v/v) solution, the solution system strongly enhanced the fluorescence. Over various small molecular species, probe B1 showed high sensitivity and selectivity for detecting FA, with a low limit of detection (0.107 mu M). Furthermore, probe B1 was successfully applied for visualizing FA in human embryonic kidney (HEK293T) cells, demonstrating its value of application in living biomedical samples. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码：180 / 184
页数：5
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