Implications of fatherhood in cystic fibrosis

被引：14

作者：

Bianco, Brooke ^{[1
,2
]}

Horsley, Alex ^{[1
,3
]}

Brennan, Amanda ^{[1
]}

机构：

[1] Manchester Univ Hosp NHS Fdn Trust, Manchester Adult CF Ctr, Manchester M23 9LT, Lancs, England

[2] Manchester Univ Hosp NHS Fdn Trust, Manchester Clin Res Facil, Manchester M23 9LT, Lancs, England

[3] Univ Manchester, Div Infect Immunol & Resp Med, Manchester M23 9LT, Lancs, England

来源：

PAEDIATRIC RESPIRATORY REVIEWS | 2019年 / 31卷

关键词：

Cystic fibrosis; Fatherhood; Lung function; Weight; Clinical decline; PREGNANCY; WOMEN;

D O I：

10.1016/j.prrv.2019.02.008

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Advances in fertility treatment mean that men with CF are increasingly able to become fathers. Here we report clinical outcomes in 22 men with CF who have become fathers for the first time. Overall mean (SD) FEV1% predicted declined from 60.1(18.0)% to 57.4(20.2)% from baseline to 1 year (p = 0.15). Weight declined from mean (SD) 70.6 kg (10.4) to 68.3 kg (10.2), p = 0.0001. Six men had an FEV1% predicted <= 40% at the time of birth: 50% died or received lung transplantation within the 12-15 month follow up period. Becoming a parent is a major life event, and as with new mothers, fathers with CF may be at risk of significant decline. (C) 2019 Published by Elsevier Ltd.

引用

页码：18 / 20

页数：3

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