Tranexamic acid gel in patients treated with oral anticoagulants

被引:3
|
作者
Ripolles-de Ramon, Jorge [1 ]
Munoz-Corcuera, Marta [1 ]
Bravo-Llatas, Carmen [1 ]
Bascones-Martinez, Antonio [1 ]
机构
[1] Univ Complutense Madrid, Fac Odontol, Dept Med & Cirugia Bucofacial, Madrid, Spain
来源
MEDICINA CLINICA | 2014年 / 143卷 / 11期
关键词
Oral anticoagulants; Tranexamic acid; Dental extraction; DENTAL EXTRACTIONS; SURGERY; WARFARIN; THROMBOEMBOLISM; PREVENTION; MANAGEMENT; MOUTHWASH;
D O I
10.1016/j.medcli.2013.07.028
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and objective: Patients treated with oral anticoagulants have increased susceptibility to bleeding, and therefore any surgical medical procedure and especially oral surgery requires a therapeutic approach that minimizes bleeding effects in these patients. Material and method: The working hypothesis was based on studies of local application of tranexamic acid after maxillofacial interventions as effective therapeutic alternative for the prevention and control of bleeding. The aim was to assess the effectiveness of the application of a gel solution tranexamic acid after tooth extraction in anticoagulated patients in terms of healing time and degree of healing. Results: The results indicate that application of tranexamic acid gel is very effective for consistency and maintenance in the place of action and shows its efficacy as a procoagulant material. Conclusions: The application of a gel solution of tranexamic acid in oral anticoagulants patients ameliorates healing time and the bleeding time within the first 48-72 h. (C) 2013 Elsevier Espana, S.L.U. All rights reserved.
引用
收藏
页码:484 / 488
页数:5
相关论文
共 50 条
  • [1] FIBRIN GLUE AND OR TRANEXAMIC ACID IN PATIENTS ON ORAL ANTICOAGULANTS UNDERGOING ORAL-SURGERY
    SACCO, R
    CARPENEDO, M
    ZINGARO, E
    THROMBOSIS AND HAEMOSTASIS, 1995, 73 (06) : 1473 - 1473
  • [2] USE OF TRANEXAMIC ACID MOUTHWASH IN DENTAL PROCEDURES IN PATIENTS TAKING ORAL ANTICOAGULANTS
    STREET, AM
    LEUNG, W
    MEDICAL JOURNAL OF AUSTRALIA, 1990, 153 (10) : 630 - 630
  • [3] Fibrin glue plus tranexamic acid mouthwashing in patients on oral anticoagulants undergoing dental
    Bucciarelli, P
    Ginelli, G
    Misani, M
    Moia, M
    THROMBOSIS AND HAEMOSTASIS, 1997, : P1517 - P1517
  • [4] Treatment of intracerebral hemorrhage in patients on direct oral anticoagulants with tranexamic acid - TICH-DOAC
    Seiffge, D.
    Peters, N.
    Sprigg, N.
    Guzman, R.
    Hert, L.
    De Marchis, G. M.
    von Hessling, A.
    Tsakiris, D.
    Nickel, C.
    Traenka, C. H.
    Bonati, L.
    Lyrer, P.
    Engelter, S.
    INTERNATIONAL JOURNAL OF STROKE, 2015, 10 : 76 - 76
  • [5] Prevalence of retinopathy in patients treated with oral anticoagulants
    Carraro, MC
    Gerli, GC
    Rossetti, L
    Staurenghi, G
    Ripamonti, C
    Uziel, L
    Orzalesi, N
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1996, 37 (03) : 498 - 498
  • [6] Ischaemic stroke in patients treated with oral anticoagulants
    Cano, L. M.
    Cardona, P.
    Quesada, H.
    Lara, B.
    Rubio, F.
    NEUROLOGIA, 2016, 31 (06): : 395 - 400
  • [7] Morbidity and mortality in patients treated with oral anticoagulants
    Navarro, Jose L.
    Cesar, Jess M.
    Fernandez, Marfa A.
    Fontcuberta, Jordi
    Reverter, Joan C.
    Gol-Freixa, Jordi
    REVISTA ESPANOLA DE CARDIOLOGIA, 2007, 60 (12): : 1226 - 1232
  • [8] FIBRIN GLUE PLUS TRANEXAMIC ACID MOUTHWASHING IN PATIENTS ON ORAL ANTICOAGULANTS UNDERGOING DENTAL EXTRACTIONS - A RANDOMIZED STUDY
    GINELLI, G
    BUCCIARELLI, P
    MISANI, M
    CARPENEDO, M
    PIGNANELLI, M
    MOIA, M
    BIANCHI, A
    THROMBOSIS AND HAEMOSTASIS, 1995, 73 (06) : 1464 - 1464
  • [9] Introducing Tranexamic Acid into a Post-Acute Facility Formulary: Two Cases in Preventing/Aborting Oral Bleeding in Patients on Oral Anticoagulants
    Sadeq, Z.
    Sakely, H.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2017, 65 : S176 - S177
  • [10] Tranexamic acid and bleeding in patients treated with non-vitamin K oral anticoagulants undergoing dental extraction: The EXTRACT-NOAC randomized clinical trial
    Ockerman, Anna
    Miclotte, Isabel
    Vanhaverbeke, Maarten
    Vanassche, Thomas
    Belmans, Ann
    Vanhove, Jan
    Meyns, Joeri
    Nadjmi, Nasser
    Van Hemelen, Geert
    Winderickx, Patrick
    Jacobs, Reinhilde
    Politis, Constantinus
    Verhamme, Peter
    PLOS MEDICINE, 2021, 18 (05)