Interposition grafts for rectovaginal fistula repair in the New Zealand white rabbit

被引:3
|
作者
Aungst, Matthew J. [1 ]
Bearss, Jeremy J. [2 ]
Lewis, Bridget S. [2 ]
Fischer, John R. [1 ]
Bonhage, Michael R. [2 ]
Wright, Johnnie, Jr. [1 ]
机构
[1] Walter Reed Army Med Ctr, Dept Obstet & Gynecol, Div Female Pelv Med & Reconstruct Surg, Washington, DC 20307 USA
[2] Armed Forces Inst Pathol, Dept Vet Pathol, Washington, DC 20306 USA
关键词
Bioprosthesis; Fistula; Models; animal; New Zealand white rabbit; Rectovaginal fistula; Xenograft; SMALL-INTESTINAL SUBMUCOSA; ENDORECTAL ADVANCEMENT FLAP; PROSTHETIC MATERIAL; SURGISIS(TM) MESH; VAGINA MODEL; DERMAL GRAFT; FASCIA LATA;
D O I
10.1007/s00192-010-1096-2
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The objective was to use an animal model to study different types of interposition grafts for rectovaginal fistula repair. Twelve New Zealand white rabbits underwent surgical creation of a rectovaginal fistula, followed by repair. Four repair techniques were studied; three with interposition grafts and one control group without a graft. Animals were euthanized at 4-week intervals and underwent gross and histologic analysis. The mean rectovaginal wall thickness was greatest in the control group (5.6 mm) and thinnest in the autologous rectus fascia (4.2 mm) and porcine small intestine submucosa (5.1 mm) groups. The polypropylene graft had a mean thickness of 5.4 mm and elicited a strong, protracted inflammatory response. All fistulas were successfully closed except one porcine small intestine submucosa repair. There is no benefit from interposition graft use for rectovaginal fistula repair in our New Zealand white rabbit model.
引用
收藏
页码:737 / 742
页数:6
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