Sex Difference in Composition of Plaques of Patients Undergoing Carotid Endarterectomy

被引：4
|
作者：
Rerkasem, Kittipan [1 ]
Gallagher, Patrick J. [2 ]
Grimble, Robert F. [3 ]
Calder, Philip C. [3 ]
Shearman, Clifford P. [4 ]
机构：
[1] Chiang Mai Univ, Dept Surg, Fac Med, Chiang Mai 50200, Thailand
[2] Southampton Gen Hosp, Dept Pathol, Southampton SO9 4XY, Hants, England
[3] Univ Southampton, Inst Human Nutr, Southampton, Hants, England
[4] Southampton Gen Hosp, Dept Vasc Surg, Southampton SO9 4XY, Hants, England
来源：
VASCULAR | 2010年 / 18卷 / 02期
关键词：
carotid plaque; fibrous; gender; lipid; sex; unstable; GENDER-DIFFERENCES; STENOSIS; SURGERY; SYMPTOMS; BENEFIT; STROKE; TRIAL;
D O I：
10.2310/6670.2010.00008
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Our study aimed to examine the hypothesis that women have more stable plaques la lower proportion of lipid component and a higher proportion of fibrous tissue) compared to men Plaque specimens of 141 consecutive carotid endarterectomy patients (60 females and 81 males) were studied Medical histories were recorded and the plasma concentrations of cholesterol and inflammatory markers were measured. We found that plaques from females had significantly less lipid than those from males (p = .01). the mean percentage of plaque lipid for women and men was 47.8% and 58 2%, respectively. Plaques from females had more fibrous tissue than those from men (p = 02) the mean percentage of fibrous tissue for women and men was 38.8% and 29 8%, respectively. This study concluded that the histology of carotid artery plaques from women appears to be more stable than that of those from men
引用
收藏
页码：77 / 81
页数：5
相关论文
共 50 条
  • [1] Selected haemostatic factors in carotid bifurcation plaques of patients undergoing carotid endarterectomy
    Migdalski, A
    Jawien, A
    Kotschy, M
    Knapik-Bieniek, A
    [J]. EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2004, 27 (02) : 172 - 179
  • [2] Sex Differences in Patients Undergoing Carotid Endarterectomy and Stenting
    Dansey, Kirsten D.
    Zettervall, Sara L.
    Soden, Peter A.
    Shean, Katie E.
    Deery, Sarah E.
    Nolan, Brian W.
    Schermerhorn, Marc L.
    [J]. JOURNAL OF VASCULAR SURGERY, 2016, 63 (06) : 83S - 84S
  • [3] Sex Differences in Patients Undergoing Carotid Endarterectomy and Stenting
    Dansey, Kirsten
    Zettervall, Sara
    Soden, Peter
    Shean, Katie
    Deery, Sarah
    Nolan, Brian
    Schermerhorn, Marc
    [J]. JOURNAL OF VASCULAR SURGERY, 2016, 64 (04) : 1185 - 1185
  • [4] Sclerostin is expressed in the atherosclerotic plaques of patients who undergoing carotid endarterectomy
    Leto, Gaetano
    D'Onofrio, Luca
    Lucantoni, Federica
    Zampetti, Simona
    Campagna, Giuseppe
    Foffi, Chiara
    Moretti, Chiara
    Carlone, Angela
    Palermo, Andrea
    Leopizzi, Martina
    Porta, Natale
    Massucci, Marco
    Lenzi, Andrea
    Bertoletti, Giovanni Battista
    Della Rocca, Carlo
    Buzzetti, Raffaella
    [J]. DIABETES-METABOLISM RESEARCH AND REVIEWS, 2019, 35 (01)
  • [5] Plant sterols in serum and in atherosclerotic plaques of patients undergoing carotid endarterectomy
    Miettinen, TA
    Railo, M
    Lepäntalo, M
    Gylling, H
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (11) : 1794 - 1801
  • [6] Cytokine Profiling of Plasma and Atherosclerotic Plaques in Patients Undergoing Carotid Endarterectomy
    Potashnikova, Daria
    Maryukhnich, Elena
    Vorobyeva, Daria
    Rusakovich, George
    Komissarov, Alexey
    Tvorogova, Anna
    Gontarenko, Vladimir
    Vasilieva, Elena
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (02)
  • [7] Hyperglycemia and Inflammatory Property of Circulating Monocytes are Associated with Inflammatory Property of Carotid Plaques in Patients Undergoing Carotid Endarterectomy
    Tanaka, Masashi
    Masuda, Shinya
    Matsuo, Yoshiyuki
    Sasaki, Yousuke
    Yamakage, Hajime
    Muranaka, Kazuya
    Wada, Hiromichi
    Hasegawa, Koji
    Tsukahara, Tetsuya
    Shimatsu, Akira
    Satoh-Asahara, Noriko
    [J]. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, 2016, 23 (10) : 1212 - 1221
  • [8] Outcome of carotid endarterectomy on the basis of patient sex: Is there a difference?
    Harthun, NL
    Cheanvechai, V
    Graham, LM
    Freischlag, JA
    Gahtan, V
    [J]. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2004, 127 (02): : 322 - 324
  • [9] Carotid Plaque Composition in Chronic Kidney Disease: A Retrospective Analysis of Patients Undergoing Carotid Endarterectomy
    Pelisek, J.
    Assadian, A.
    Sarkar, O.
    Eckstein, H. H.
    Frank, H.
    [J]. EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2010, 39 (01) : 11 - 16
  • [10] Carotid plaque volume in patients undergoing carotid endarterectomy
    Ball, S.
    Rogers, S.
    Kanesalingam, K.
    Taylor, R.
    Katsogridakis, E.
    McCollum, C.
    [J]. BRITISH JOURNAL OF SURGERY, 2018, 105 (03) : 262 - 269
12345