SH2 domains - A question of independence

被引:4
|
作者
Wandless, TJ
机构
[1] Department of Chemistry, Stanford University, Stanford
关键词
D O I
10.1016/S0960-9822(02)00440-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The three-dimensional structures of parts of two enzymes that contain tandem Src homology 2 (SH2) domains have recently been determined. The structures suggest how the SH2 domains function in concert to regulate enzymatic activity and localization.
引用
收藏
页码:125 / 127
页数:3
相关论文
共 50 条
  • [1] SH2 AND SH3 DOMAINS
    PAWSON, T
    SCHLESSINGER, J
    CURRENT BIOLOGY, 1993, 3 (07) : 434 - 442
  • [2] The druggability of SH2 domains unmasked
    Hantschel, Oliver
    NATURE CHEMICAL BIOLOGY, 2024, 20 (03) : 271 - 272
  • [3] Dual specificity of SH2 domains
    Kirsty Minton
    Nature Reviews Molecular Cell Biology, 2016, 17 : 266 - 266
  • [4] The druggability of SH2 domains unmasked
    Oliver Hantschel
    Nature Chemical Biology, 2024, 20 : 271 - 272
  • [5] STRUCTURES OF SH2 AND SH3 DOMAINS
    KURIYAN, J
    COWBURN, D
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 1993, 3 (06) : 828 - 837
  • [6] Functions of SH2 and SH3 domains
    Mayer, BJ
    Gupta, R
    PROTEIN MODULES IN SIGNAL TRANSDUCTION, 1998, 228 : 1 - 22
  • [7] STRUCTURE AND FUNCTION OF SH2 DOMAINS
    MARENGERE, LEM
    PAWSON, T
    JOURNAL OF CELL SCIENCE, 1994, : 97 - 104
  • [8] Molecular recognition by SH2 domains
    Bradshaw, JM
    Waksman, G
    PROTEIN MODULES AND PROTEIN-PROTEIN INTERACTIONS, 2003, 61 : 161 - 210
  • [9] Interactions between SH2 and SH3 domains
    Vihinen, M
    Smith, CIE
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 242 (02) : 351 - 356
  • [10] SH2 SH3 - EXPLORATION OF NEW DOMAINS
    MOORE, B
    SEROUSSI, G
    JOCHIM, B
    M S-MEDECINE SCIENCES, 1993, 9 (6-7): : 788 - 790