This study is to investigate the characteristic features of Acanthamoeba keratitis (AK) that differentiating it from herpetic epithelial keratitis (HEK) using anterior segment optical coherence tomography (AS-OCT). Medical records of three eyes of each AK and herpetic keratitis who had AS-OCT examination were reviewed in this study. Slit-lamp biomicroscopy and AS-OCT was performed on the initial visit and on every follow-up visits in all patients. In all three AK cases, reflective bands in the corneal stroma that correspond to the area of radial keratoneuritis were observed. The depth of the reflective bands varied in each case. After AK treatment, slit-lamp biomicroscopy confirmed that radial keratoneuritis had resolved and AS-OCT confirmed that reflective bands in the corneal stroma had also disappeared in all patients. Unlike the AS-OCT results found in AK, highly reflective HEK lesions were observed only in the subepithelial area, not in the stroma. AS-OCT seems to be helpful analyzing the specific depth of the lesion which enables to distinguish AK from HEK.
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Department of Ophthalmology,School of Medicine,Gyeongsang National University
Institute of Health Science,Gyeongsang National UniversityDepartment of Ophthalmology,School of Medicine,Gyeongsang National University
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Kanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
Yamazaki, Natsuko
Kobayashi, Akira
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Kanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
Kobayashi, Akira
Yokogawa, Hideaki
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Kanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
Yokogawa, Hideaki
Ishibashi, Yasuhisa
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Tsukuba Hosp, Dept Ophthalmol, Tsukuba, Ibaraki, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
Ishibashi, Yasuhisa
Oikawa, Yosaburo
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Kanazawa Med Univ, Dept Med Zool, Kahoku, Ishikawa 92002, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
Oikawa, Yosaburo
Tokoro, Masaharu
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Kanazawa Univ, Grad Sch Med Sci, Dept Parasitol, Kanazawa, Ishikawa 9208641, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
Tokoro, Masaharu
Sugiyama, Kazuhisa
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Kanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, JapanKanazawa Univ, Grad Sch Med Sci, Dept Ophthalmol, Kanazawa, Ishikawa 9208641, Japan
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Univ Southampton, Southampton Gen Hosp, Eye Unit, Southampton SO16 6YD, Hants, EnglandUniv Southampton, Southampton Gen Hosp, Eye Unit, Southampton SO16 6YD, Hants, England
Konstantopoulos, Aris
Kuo, Jennifer
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Univ Southampton, Southampton Gen Hosp, Eye Unit, Southampton SO16 6YD, Hants, EnglandUniv Southampton, Southampton Gen Hosp, Eye Unit, Southampton SO16 6YD, Hants, England
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Assiut Univ, Dept Ophthalmol, Fac Med, Assiut, EgyptAssiut Univ, Dept Ophthalmol, Fac Med, Assiut, Egypt
Soliman, Wael
Nassr, Mohamed A.
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Assiut Univ, Dept Ophthalmol, Fac Med, Assiut, Egypt
North West Anglia NHS Fdn Trust, Peterborough, Cambs, EnglandAssiut Univ, Dept Ophthalmol, Fac Med, Assiut, Egypt
Nassr, Mohamed A.
Abdelazeem, Khaled
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Assiut Univ, Dept Ophthalmol, Fac Med, Assiut, EgyptAssiut Univ, Dept Ophthalmol, Fac Med, Assiut, Egypt
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Sharma, Namrata
Singhal, Deepali
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Singhal, Deepali
Maharana, Prafulla Kumar
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Maharana, Prafulla Kumar
Agarwal, Tushar
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Agarwal, Tushar
Sinha, Rajesh
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Sinha, Rajesh
Satpathy, Gita
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All India Inst Med Sci, Dept Ocular Microbiol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Satpathy, Gita
Bageshwar, Lalit Mohan Singh
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India
Bageshwar, Lalit Mohan Singh
Titiyal, Jeewan S.
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All India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, IndiaAll India Inst Med Sci, Dept Ophthalmol, Dr Rajendra Prasad Ctr Ophthalm Sci, New Delhi, India