A computational simulation of the effect of hybrid treatment for thoracoabdominal aortic aneurysm on the hemodynamics of abdominal aorta

被引:17
|
作者
Wen, Jun [1 ]
Yuan, Ding [2 ]
Wang, Qingyuan [3 ]
Hu, Yao [4 ]
Zhao, Jichun [2 ]
Zheng, Tinghui [3 ]
Fan, Yubo [5 ]
机构
[1] Southwest Univ Sci & Technol, Sch Civil Engn & Architecture, Mianyang 621010, Sichuan, Peoples R China
[2] Sichuan Univ, Vasc Surg Dept, West China Sch Med, Chengdu 610041, Peoples R China
[3] Sichuan Univ, Dept Appl Mech, Chengdu 610065, Peoples R China
[4] Sichuan Univ, West China Hosp, Regenerat Med Res Ctr, Chengdu 610041, Peoples R China
[5] Beihang Univ, Sch Biol Sci & Med Engn, Minist Educ, Key Lab Biomech & Mech, Beijing 100191, Peoples R China
来源
SCIENTIFIC REPORTS | 2016年 / 6卷
基金
中国国家自然科学基金;
关键词
ENDOVASCULAR REPAIR; FLOW; DISEASE; GRAFTS;
D O I
10.1038/srep23801
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Hybrid visceral-renal debranching procedures with endovascular repair have been proposed as an appealing technique to treat conventional thoracoabdominal aortic aneurysm (TAAA). This approach, however, still remained controversial because of the non-physiological blood flow direction of its retrograde visceral revascularization (RVR) which is generally constructed from the aortic bifurcation or common iliac artery. The current study carried out the numerical simulation to investigate the effect of RVR on the hemodynamics of abdominal aorta. The results indicated that the inflow sites for the RVR have great impact on the hemodynamic performance. When RVR was from the distal aorta, the perfusion to visceral organs were adequate but the flow flux to the iliac artery significantly decreased and a complex disturbed flow field developed at the distal aorta, which endangered the aorta at high risk of aneurysm development. When RVR was from the right iliac artery, the abdominal aorta was not troubled with low WSS or disturbed flow, but the inadequate perfusion to the visceral organs reached up to 40% and low WSS and flow velocity predominated appeared at the right iliac artery and the grafts, which may result in the stenosis in grafts and aneurysm growth on the host iliac artery.
引用
收藏
页数:9
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