We develop methods for analyzing discrete multivariate longitudinal data and apply them to functional disability data on the U.S. elderly population from the National Long Term Care Survey (NLTCS), 1982-2004. Our models build on a Mixed Membership framework, in which individuals are allowed multiple membership on a set of extreme profiles characterized by time-dependent trajectories of progression into disability. We also develop an extension that allows us to incorporate birth-cohort effects, in order to assess inter-generational changes. Applying these methods, we find that most individuals follow trajectories that imply a late onset of disability, and that younger cohorts tend to develop disabilities at a later stage in life compared to their elders.
机构:
Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USARush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USA
Capuano, Ana W.
Wilson, Robert S.
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Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USARush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USA
Wilson, Robert S.
Leurgans, Sue E.
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机构:
Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USARush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USA
Leurgans, Sue E.
Dawson, Jeffrey D.
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Univ Iowa, Dept Biostat, Iowa City, IA USARush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USA
Dawson, Jeffrey D.
Bennett, David A.
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Rush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USARush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USA
Bennett, David A.
Hedeker, Donald
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Univ Chicago, Dept Publ Hlth Sci, Biostat, Chicago, IL 60637 USARush Univ, Rush Alzheimers Dis Ctr, Med Ctr, 600 South Paulina,Suite 1023B, Chicago, IL 60612 USA
机构:
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Molsberry, Samantha A.
Lecci, Fabrizio
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Carnegie Mellon Univ, Dept Stat, Pittsburgh, PA 15213 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Lecci, Fabrizio
Kingsley, Lawrence
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Univ Pittsburgh, Grad Sch Publ Hlth, Infect Dis & Microbiol, Pittsburgh, PA USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Kingsley, Lawrence
Junker, Brian
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机构:
Carnegie Mellon Univ, Dept Stat, Pittsburgh, PA 15213 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Junker, Brian
Reynolds, Sandra
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机构:
Johns Hopkins Univ, Dept Epidemiol, Bloomberg Sch Publ Hlth, Baltimore, MD USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Reynolds, Sandra
Goodkin, Karl
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AIDS Healthcare Fdn, Los Angeles, CA USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Goodkin, Karl
Levine, Andrew J.
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Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Levine, Andrew J.
Martin, Eileen
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机构:
Rush Univ, Sch Med, Dept Psychiat, Chicago, IL 60612 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Martin, Eileen
Miller, Eric N.
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机构:
Univ Calif Los Angeles, Dept Psychiat, Los Angeles, CA 90024 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Miller, Eric N.
Munro, Cynthia A.
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机构:
Johns Hopkins Univ, Sch Med, Dept Psychiat, Baltimore, MD 21205 USA
Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Munro, Cynthia A.
Ragin, Ann
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Northwestern Univ, Dept Radiol, Evanston, IL USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Ragin, Ann
Sacktor, Ned
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机构:
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Sacktor, Ned
Becker, James T.
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机构:
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Psychol, Pittsburgh, PA 15260 USAUniv Pittsburgh, Dept Psychiat, Pittsburgh, PA USA