Deletion of 3′-CBFB gene in association with an inversion (16)(p13q22) and a loss of the Y chromosome in a 2-year-old child with acute myelogenous leukemia-M4

被引：9
|
作者：
Batanian, JR
Huang, YF
Fallon, R
机构：
[1] St Louis Univ, Cardinal Glennon Childrens Hosp, Dept Pediat, Mol Cytogenet Lab, St Louis, MO 63104 USA
[2] St Louis Univ, Pediat Res Inst, Dept Pediat & Hematol Oncol, St Louis, MO 63103 USA
来源：
CANCER GENETICS AND CYTOGENETICS | 2000年 / 121卷 / 02期
关键词：
D O I：
10.1016/S0165-4608(00)00251-X
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Inversion 16(p13q22) is most commonly associated with acute myelomonocytic leukemia with abnormal eosinophils (M4). III association with this inversion, a proximal deletion at the 16p13 primary arm breakpoint occurs in 20% of cases. We report on a first case of inversion IG with a distal deletion at the primary arm breakpoint 16q22, detected by using the fluorescent-labeled dual-color probe CBFB. (C) 2000 Elsevier Science Inc. All rights reserved.
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收藏
页码：216 / 219
页数：4
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