Efficacy and safety of trifluridine/tipiracil (FTD/TPI) in patients (pts) with metastatic gastric cancer (mGC) with or without prior gastrectomy: Results from a phase III study (TAGS).

被引:1
|
作者
Ilson, David H.
Prokharau, Aliaksandr
Arkenau, Hendrik-Tobias
Ghidini, Michele
Fujitani, Kazumasa
Van Cutsem, Eric
Thuss-Patience, Peter C.
Beretta, Giordano D.
Mansoor, Wasat
Zhavrid, Edvard
Alsina, Maria
George, Ben
Catenacci, Daniel V. T.
Winkler, Robert E.
Makris, Lukas
Doi, Toshihiko
Shitara, Kohei
机构
[1] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[2] Minsk City Clin Oncol Dispensary, Minsk, BELARUS
[3] Sarah Cannon Res Inst, London, England
[4] UCL, London, England
[5] Azienda Osped Cremona, Cremona, Italy
[6] Osaka Gen Med Ctr, Osaka, Japan
[7] Univ Hosp, Leuven, Belgium
[8] Katholieke Univ Leuven, Leuven, Belgium
[9] Charite Univ Med Berlin, Berlin, Germany
[10] Humanitas Gavazzeni, Bergamo, Italy
[11] Christie NHS Fdn Trust Hosp, Manchester, Lancs, England
[12] Alexandrov Natl Canc Ctr Belarus, Minsk, BELARUS
[13] Vall dHebron Univ Hosp, Barcelona, Spain
[14] Vall dHebron Inst Oncol, Barcelona, Spain
[15] Med Coll Wisconsin, Milwaukee, WI 53226 USA
[16] Univ Chicago, Med Ctr & Biol Sci, Chicago, IL 60637 USA
[17] Taiho Oncol Inc, Princeton, NJ USA
[18] Stathmi Inc, New Hope, PA USA
[19] Hosp East, Natl Canc Ctr, Chiba, Japan
关键词
D O I
10.1200/JCO.2019.37.4_suppl.3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
3
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Efficacy and safety of trifluridine/tipiracil (FTD/TPI) in patients (pts) with metastatic gastric cancer (mGC) with or without prior gastrectomy: results from a phase III study (TAGS)
    Thuss-Patience, P.
    Lorenzen, S.
    Ettrich, T.
    Karthaus, M.
    Ilson, D. H.
    Prokharau, A.
    Arkenau, H-T.
    Ghidini, M.
    Fujitani, K.
    Van Cutsem, E.
    Beretta, G. D.
    Mansoor, W.
    Zhavrid, E.
    Alsina, M.
    George, B.
    Catenacci, D. V. T.
    Makris, L.
    Doi, T.
    Shitara, K.
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 : 307 - 308
  • [2] Efficacy and safety of trifluridine/tipiracil (FTD/TPI) in European patients with heavily pretreated metastatic gastric cancer (mGC): An analysis of the TAGS study
    Alsina, M.
    Tabernero, J.
    Arkenau, H-T.
    Squadroni, M.
    Doi, T.
    Faustino, C.
    Ghidini, M.
    Mansoor, W.
    Shitara, K.
    Van Cutsem, E.
    Causse-Amellal, N.
    Leger, C.
    Skanji, D.
    Ilson, D.
    ANNALS OF ONCOLOGY, 2019, 30
  • [3] Analysis of symptoms and functional HRQoL scales in TAGS, a phase III trial of trifluridine/tipiracil (FTD/TPI) in metastatic gastric cancer (mGC).
    Alsina, Maria
    Tabernero, Josep
    Shitara, Kohei
    Doi, Toshihiko
    Dvorkin, Mikhail
    Mansoor, Wasat
    Arkenau, Hendrik-Tobias
    Prokharau, Aliaksandr
    Ghidini, Michele
    Faustino, Catia
    Gorbunova, Vera
    Zhavrid, Edvard
    Nishikawa, Kazuhiro
    Ando, Takayuki
    Yalcin, Suayib
    Van Cutsem, Eric
    Skanji, Donia
    Leger, Catherine
    Sabater, Javier
    Ilson, David H.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [4] Overall survival results from a phase III trial of trifluridine/tipiracil (FTD/TPI) vs placebo in patients (Pts) with metastatic gastric cancer refractory to standard therapies (TAGS)
    Shitara, K.
    Tabernero, J.
    Dvorkin, M.
    Mansoor, W.
    Arkenau, H-T.
    Prokharau, A.
    Alsina, M.
    Ghidini, M.
    Faustino, C.
    Gorbunova, V.
    Zhavrid, E.
    Nishikawa, K.
    Hosokawa, A.
    Ganea, D.
    Yalcin, S.
    Fujitani, K.
    Beretta, G.
    Winkler, R.
    Doi, T.
    Ilson, D. H.
    ANNALS OF ONCOLOGY, 2018, 29 : 55 - 55
  • [5] Trifluridine/tipiracil (FTD/TPI) in patients (pts) aged ≥65 years with metastatic gastric/gastroesophageal junction cancer (mGC/mGEJC): Subgroup analysis from TAGS.
    Shitara, Kohei
    Doi, Toshihiko
    Hosaka, Hisashi
    Thuss-Patience, Peter C.
    Santoro, Armando
    Jimenez-Fonseca, Paula
    Longo, Federico
    Ozyilkan, Ozgur
    Cicin, Irfan
    Park, David
    Tejani, Mohamedtaki Abdulaziz
    Zaanan, Aziz
    Bilancia, Domenico
    Pericay, Carles
    Ozguroglu, Mustafa
    Alsina, Maria
    Makris, Lukas
    McGuigan, Sandra
    Ilson, David H.
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [6] Pooled safety analysis from phase 3 studies of trifluridine/tipiracil (FTD/TPI) in patients (pts) with metastatic gastric/gastroesophageal junction cancer (mGC/mGEJC) and metastatic colorectal cancer (mCRC).
    Van Cutsem, Eric
    Hochster, Howard S.
    Shitara, Kohei
    Mayer, Robert J.
    Ohtsu, Atsushi
    Falcone, Alfredo
    Yoshino, Takayuki
    Doi, Toshihiko
    Ilson, David H.
    Arkenau, Hendrik-Tobias
    George, Ben
    McGuigan, Sandra
    Makris, Lukas
    Tabernero, Josep
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [7] Trifluridine/tipiracil (FTD/TPI) in patients (pts) with metastatic gastroesophageal junction cancer (mGEJC): Subgroup analysis from TAGS.
    Mansoor, Wasat
    Arkenau, Hendrik-Tobias
    Alsina, Maria
    Shitara, Kohei
    Tejani, Mohamedtaki Abdulaziz
    Thuss-Patience, Peter C.
    Cuffe, Sinead
    Dvorkin, Mikhail
    Park, David
    Ando, Takayuki
    Van Den Eynde, Marc
    Beretta, Giordano D.
    Zaniboni, Alberto
    Doi, Toshihiko
    Tabernero, Josep
    Ilson, David H.
    Makris, Lukas
    McGuigan, Sandra
    Van Cutsem, Eric
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [8] The impact of prior therapies on outcomes with trifluridine/tipiracil (FTD/TPI) in the phase III TAGS trial.
    Shitara, Kohei
    George, Ben
    Taieb, Julien
    Sundar, Raghav
    Fakih, Marwan
    Makris, Lukas
    Benhadji, Karim A.
    Ghidini, Michele
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (03)
  • [9] Safety of trifluridine/tipiracil (FTD/TPI) in elderly patients with metastatic colorectal cancer.
    Mayer, Robert J.
    Hochster, Howard S.
    Cohen, Steven J.
    Winkler, Robert
    Makris, Lukas
    Grothey, Axel
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (04)
  • [10] Safety and efficacy of trifluridine/tipiracil (FTD/TPI) in metastatic colorectal cancer (mCRC) patients according to previous treatment with regorafenib in the international phase IIIb PRECONNECT study
    Taieb, J.
    Falcone, A.
    Lonardi, S.
    Price, T. J.
    Bachet, J-B.
    Wyrwicz, L.
    Ciardiello, F.
    Becquart, M.
    Mounedji, N.
    Van Cutsem, E.
    ANNALS OF ONCOLOGY, 2018, 29 : 155 - 155