The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease

被引：25
|
作者：
Sabatine, MS
Jang, IK
机构：
[1] Massachusetts Gen Hosp, Div Cardiol, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Boston, MA USA
来源：
AMERICAN JOURNAL OF MEDICINE | 2000年 / 109卷 / 03期
关键词：
D O I：
10.1016/S0002-9343(00)00474-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Platelet membrane glycoprotein IIb/IIIa inhibitors, a new class of potent antiplatelet agents, have been used in the treatment of acute coronary syndromes as well as in the prevention of complications after percutaneous coronary interventions. Approximately 50,000 patients with coronary artery disease have been enrolled in randomized studies of glycoprotein IIb/IIIa inhibitors. The purpose of this article is to review the pharmacology of glycoprotein IIb/IIIa inhibitors, the results of the clinical trials using these agents, and their current use in percutaneous coronary interventions and the treatment of acute coronary syndromes. (C) 2000 by Excerpta Medica, Inc.
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收藏
页码：224 / 237
页数：14
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