Dielectric modulation of biological water -: art. no. 228104

被引:89
|
作者
Despa, F
Fernández, A
Berry, RS
机构
[1] Univ Chicago, Dept Chem, Chicago, IL 60637 USA
[2] Indiana Univ, Sch Informat, Indianapolis, IN 46202 USA
[3] Indiana Univ, Sch Med, INGEN Ctr Computat Biol & Bioinformat, Indianapolis, IN 46202 USA
基金
美国国家科学基金会;
关键词
D O I
10.1103/PhysRevLett.93.228104
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We show that water constrained by vicinal hydrophobes undergoes a librational dynamics that lowers the dielectric susceptibility and induces a "redshift" of the relaxation frequency in the hydration shell. The results shed light on the way proteins enhance their intramolecular interactions as they fold or associate.
引用
收藏
页码:228104 / 1
页数:4
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