LEPTIN AND NEUTROPHIL ACTIVATING PROTEIN 2 PROMOTE MESENCHYMAL STEM CELLS SENESCENCE THROUGH THE ACTIVATION OF PI3K/AKT PATHWAY IN SYSTEMIC LUPUS ERYTHEMATOSUS

被引:0
|
作者
Chen, H. [1 ]
Feng, X. [1 ]
Sun, L. [1 ]
机构
[1] Nanjing Univ, Sch Med, Affiliated Drum Tower Hosp, Dept Rheumatol, Nanjing 210008, Jiangsu, Peoples R China
关键词
D O I
10.1136/annrheumdis-2014-eular.2195
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
THU0050
引用
收藏
页码:193 / 193
页数:1
相关论文
共 50 条
  • [1] Leptin and neutrophil activating protein 2 promote mesenchymal stem cells senescence through the activation of PI3K/Akt pathway in systemic lupus erythematosus
    Chen, H.
    Feng, X.
    Sun, L.
    BONE MARROW TRANSPLANTATION, 2015, 50 : S146 - S146
  • [2] Leptin and Neutrophil-Activating Peptide 2 Promote Mesenchymal Stem Cell Senescence Through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Patients With Systemic Lupus Erythematosus
    Chen, Haifeng
    Shi, Bingyu
    Feng, Xuebing
    Kong, Wei
    Chen, Weiwei
    Geng, Linyu
    Chen, Jinyun
    Liu, Rui
    Li, Xia
    Chen, WanJun
    Gao, Xiang
    Sun, Lingyun
    ARTHRITIS & RHEUMATOLOGY, 2015, 67 (09) : 2383 - 2393
  • [4] Expression of human telomerase reverse transcriptase mediates the senescence of mesenchymal stem cells through the PI3K/AKT signaling pathway
    Zhao, Qiang
    Wang, Xue-Yao
    Yu, Xiao-Xia
    Zhai, Ying-Xian
    He, Xu
    Wu, Shan
    Shi, Ying-Ai
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2015, 36 (03) : 857 - 864
  • [5] Bone marrow mesenchymal stem cells promote uterine healing by activating the PI3K/AKT pathway and modulating inflammation in rat models
    Yang, Jing
    Yuan, Jun
    Wen, Yan-Qing
    Wu, Li
    Liao, Jiu-Jiang
    Qi, Hong-Bo
    WORLD JOURNAL OF STEM CELLS, 2025, 17 (01):
  • [6] Leonurine Protects Bone Mesenchymal Stem Cells from Oxidative Stress by Activating Mitophagy through PI3K/Akt/mTOR Pathway
    Zhao, Bingkun
    Peng, Qian
    Wang, Dan
    Zhou, Rong
    Wang, Raorao
    Zhu, Yizhun
    Qi, Shengcai
    CELLS, 2022, 11 (11)
  • [7] Deciphering of PI3K/Akt/mTOR pathway in peripheral T lymphocytes of systemic lupus erythematosus patients
    Pistol, Gina
    Banica, Leontina
    Besliu, Alina
    Tanaseanu, Stefanita
    Matache, Cristiana
    Stefanescu, Maria
    JOINT BONE SPINE, 2007, 74 (02) : 216 - 216
  • [8] Systemic Lupus Erythematosus: the involvement of PI3K/Akt/mTOR pathway in cellular cycle and in early apoptosis
    Besliu, A.
    Banica, L.
    Matache, C.
    Tanaseanu, S.
    Ionescu, R.
    Dumitrache, S.
    Stavaru, C.
    Stefanescu, M.
    JOINT BONE SPINE, 2008, 75 (02) : 246 - 246
  • [9] HBx drives alpha fetoprotein expression to promote initiation of liver cancer stem cells through activating PI3K/AKT signal pathway
    Zhu, Mingyue
    Li, Wei
    Lu, Yan
    Dong, Xu
    Lin, Bo
    Chen, Yi
    Zhang, Xueer
    Guo, Junli
    Li, Mengsen
    INTERNATIONAL JOURNAL OF CANCER, 2017, 140 (06) : 1346 - 1355
  • [10] Mesenchymal stem cells from perinatal tissues promote diabetic wound healing via PI3K/AKT activation
    Huang, Jiawei
    Deng, Qingwen
    Tsang, Lai Ling
    Chang, Guozhu
    Guo, Jinghui
    Ruan, Ye Chun
    Wang, Chi Chiu
    Li, Gang
    Chan, Hon Fai
    Zhang, Xiaohu
    Jiang, Xiaohua
    STEM CELL RESEARCH & THERAPY, 2025, 16 (01)