Overlap domain decomposition method for bioluminescence tomography (BLT)

被引：4

作者：

Wang, Tao ^{[2
,3
]}

Gao, Shuping ^{[2
,3
]}

Zhang, Ling ^{[2
,3
]}

Wu, Yan ^{[3
]}

He, Xiaowei ^{[3
]}

Hou, Yanbin ^{[3
]}

Huang, Heyu ^{[3
]}

Tian, Jie ^{[1
,3
]}

机构：

[1] Chinese Acad Sci, Med Image Proc Grp, Inst Automat, Beijing 100080, Peoples R China

[2] Xidian Univ, Dept Appl Math, Xian 710071, Shaanxi, Peoples R China

[3] Xidian Univ, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China

来源：

INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING | 2010年 / 26卷 / 05期

关键词：

tomography; image reconstruction techniques; overlap domain decomposition method; finite element method; symmetric positive definite matrix; SCHWARZ METHODS; LIGHT; RECONSTRUCTION; CONVERGENCE; ALGORITHM;

D O I：

10.1002/cnm.1242

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Bioluminescence tomography (BLT) allows in vivo localization and quantification of bioluminescent sources inside a small animal to reveal various molecular and cellular activities. In this paper, the overlap domain decomposition method (ODDM) of BLT is proposed, which refers to divide and conquer techniques for solving BLT by iteratively solving sub-problems on smaller sub-domains. Here, two triangulations of the region are adopted. We can obtain the photon density distribution on the object surface, as well as reconstruct the position of the light source by using ODDM and genetic algorithm. The numerical simulations have shown that ODDM is computationally efficient and fairly robust. Copyright (C) 2009 John Wiley & Sons, Ltd.

引用

页码：511 / 523

页数：13

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