Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit

被引：31
|
作者：
Omidizadeh, Alireza [1 ]
Yusof, Rokiah Mohd [1 ]
Roohinejad, Shahin [2 ]
Ismail, Amin [1 ]
Abu Bakar, Mohd Zuki [3 ]
Bekhit, Alaa El-Din A. [2 ]
机构：
[1] Univ Putra Malaysia, Fac Med & Hlth Sci, Dept Nutr & Dietet, Serdang, Malaysia
[2] Univ Otago, Dept Food Sci, Dunedin 9054, New Zealand
[3] Univ Putra Malaysia, Fac Vet Med, Dept Anat, Serdang, Malaysia
来源：
RSC ADVANCES | 2014年 / 4卷 / 108期
关键词：
HIGH-FRUCTOSE DIET; DIABETES-MELLITUS; ANTIOXIDANT ACTIVITY; INSULIN-RESISTANCE; GLUCOSE-TOLERANCE; OXIDATIVE STRESS; LIPID-METABOLISM; RAT MODEL; FIBER; HYPERTENSION;
D O I：
10.1039/c4ra10789f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
This study investigated the anti-insulin resistant activity of red pitaya (Hylocereus polyrhizus) fruit. Fresh pitaya along with two heat-processed pitaya samples with different proportions of phenolic contents, scavenging activities, and soluble dietary fibers were tested in insulin resistant rats over 6 weeks of treatment in a cause-effect study to investigate the anti-insulin resistant components of red pitaya. The results showed that fresh pitaya significantly (p < 0.05) attenuated the insulin resistance, hypertriglyceridemia and atherosclerotic changes induced by fructose supplement in rats. Thermally-treated pitaya at 95 degrees C for 30 min (containing a low antioxidant content) significantly (p < 0.05) improved hyperinsulinemia. Thermally-treated pitaya at 105 degrees C for 60 min (containing a low antioxidant and soluble dietary fiber content) fed to rats had no significant effect on insulin resistance, dyslipidemia and atherogenesis. Based on this study, the anti-insulin resistant effect of red pitaya can be attributed to its antioxidant and soluble dietary fiber contents.
引用
收藏
页码：62978 / 62986
页数：9
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