Patient relevant endpoint mobility: Assessment of driving performance in dementia diseases

Mobility is central to the everyday functionality of older people but poses particular challenges to road safety in the case of dementia. Whether a driver with dementia is still able to drive depends on the type and severity of the dementia syndrome in question. There is international consensus that in most cases drivers with moderate or severe dementia are no longer fit to drive. However, the various forms of dementia differ with regard to the expression of driving-relevant cognitive and noncognitive symptoms producing different effects on driving safety. In particular, the group of non-Alzheimer dementias is associated with driving-related impairments. Hence, particularly those drivers should be subjected to close monitoring and mobility counseling early on in the course of the disease.