Immunomodulatory proteins of orthopoxviruses

被引：19
|
作者：
Shchelkunov, SN [1 ]
机构：
[1] Vector Minist Hlth Russian Federat, State Res Ctr Virol & Biotechnol, Inst Mol Biol, Koltsov 630559, Novosibirsk Reg, Russia
来源：
MOLECULAR BIOLOGY | 2003年 / 37卷 / 01期
关键词：
orthopoxviruses; variola virus; monkeypox virus; cowpox virus; vaccinia virus; immunomodulation; genome; computer analysis;
D O I：
10.1023/A:1022324511384
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The review considers recent data on the structural-functional organization of the genome of ortho-poxviruses pathogenic for humans, including the variola, monkeypox, cowpox, and vaccinia viruses. Emphasis was placed on the structure of molecular virulence factors that suppress the inflammatory reactions, immune response, and interferon effects induced by virus infection.
引用
收藏
页码：37 / 48
页数：12
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