Polymorphisms in the estrogen receptor beta gene and risk of breast cancer:: no association

被引：35
|
作者：
Försti, A [1 ]
Zhao, CY [1 ]
Israelsson, E [1 ]
Dahlman-Wright, K [1 ]
Gustafsson, JÅ [1 ]
Hemminki, K [1 ]
机构：
[1] Karolinska Inst, Novum, Dept Biosci, SE-14157 Huddinge, Sweden
来源：
BREAST CANCER RESEARCH AND TREATMENT | 2003年 / 79卷 / 03期
关键词：
breast cancer; estrogen receptor beta; polymorphism;
D O I：
10.1023/A:1024020609833
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Polymorphisms in the estrogen receptor beta (ERbeta) gene may influence the cellular growth regulating effects of estradiol. In this first association study about breast cancer risk and polymorphisms in the ERbeta gene we have screened 219 Finnish sporadic breast cancer cases and 248 ethnically matched male controls. No difference in the allele distribution of the six studied polymorphisms was found between the breast cancer and control groups.
引用
收藏
页码：409 / 413
页数：5
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