Transgenic Expression of hCD47 on Vessels in Porcine GalTKO Lung Grafts in Baboons may Mitigate Acute Vascular Rejection in Baboons: Up to 13 Days Graft Survival in Baboons

被引：0

|

作者：

Watanabe, Hironosuke ^{[1
]}

Nomura, Shunichiro ^{[1
]}

Sahara, Hisashi ^{[2
]}

Pomposelli, Thomas ^{[1
]}

Ariyoshi, Yuichi ^{[1
]}

Boyd, Lennan K. ^{[1
]}

Ekanayake-Alper, Dilrukshi K. ^{[1
]}

Tanabe, Tatsu ^{[1
]}

Glor, Harrison C. ^{[1
]}

Arn, Scott ^{[1
]}

Hawley, Robert J. ^{[1
]}

Shimizu, Akira ^{[2
]}

Ayares, David ^{[4
]}

Lorber, Marc I. ^{[3
]}

Sykes, Megan ^{[1
]}

Sachs, David H. ^{[1
]}

Yamada, Kazuhiko ^{[1
]}

机构：

[1] Columbia Univ, Med Ctr, CCTI Surg, New York, NY USA

[2] Kagoshima Univ, Dept Organ Replacement & Xenotransplantat Surg, Kagoshima, Japan

[3] Lung BioTechnol PBC, Silver Spring, MD USA

[4] Revivicor, Blacksburg, VA USA

来源：

TRANSPLANTATION | 2018年 / 102卷

关键词：

D O I：

10.1097/01.tp.0000543035.62185.da

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

526.3

引用

收藏

页码：S313 / S313

页数：1

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[2] Histologically proven survival of porcine lung xenografts in baboons for up to 10 days using double transgenic hCD47/hCD55 GalT-KO donors
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[3] Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival
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