Microbiota-Gut-Brain Axis and Cognitive Function

被引：127
|
作者：
Gareau, Melanie G. [1 ]
机构：
[1] Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
来源：
MICROBIAL ENDOCRINOLOGY: THE MICROBIOTA-GUT-BRAIN AXIS IN HEALTH AND DISEASE | 2014年 / 817卷
关键词：
IRRITABLE-BOWEL-SYNDROME; INTESTINAL BARRIER FUNCTION; MEDIAL PREFRONTAL CORTEX; MATERNAL SEPARATION; ADULT RATS; LACTOBACILLUS-HELVETICUS; HEPATIC-ENCEPHALOPATHY; MYCOBACTERIUM-VACCAE; COLONIC DYSFUNCTION; EMOTIONAL BEHAVIOR;
D O I：
10.1007/978-1-4939-0897-4_16
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recent studies have demonstrated a clear association between changes in the microbiota and cognitive behavior. Intestinal dysbiosis, as modeled using GF mice (containing no microbiota), bacterial infection with an enteric pathogen, and administration of probiotics, can modulate cognitive behavior including learning and memory. This chapter will highlight recent findings in both human and animal studies indicating how changes in the composition and diversity of the microbiota can impact behavior and brain physiology in both disease states and in health. Cognitive behavior can not only be affected in cases of intestinal disease, but also manifests changes in extra-intestinal disease conditions.
引用
收藏
页码：357 / 371
页数：15
相关论文
共 50 条
  • [1] THE MICROBIOTA-GUT-BRAIN AXIS
    Cryan, John F.
    O'Riordan, Kenneth J.
    Cowan, Caitlin S. M.
    Sandhu, Kiran V.
    Bastiaanssen, Thomaz F. S.
    Boehme, Marcus
    Codagnone, Martin G.
    Cussotto, Sofia
    Fulling, Christine
    Golubeva, Anna V.
    Guzzetta, Katherine E.
    Jaggar, Minal
    Long-Smith, Caitriona M.
    Lyte, Joshua M.
    Martin, Jason A.
    Molinero-Perez, Alicia
    Moloney, Gerard
    Morelli, Emanuela
    Morillas, Enrique
    O'Connor, Rory
    Cruz-Pereira, Joana S.
    Peterson, Veronica L.
    Rea, Kieran
    Ritz, Nathaniel L.
    Sherwin, Eoin
    Spichak, Simon
    Teichman, Emily M.
    van de Wouw, Marcel
    Ventura-Silva, Ana Paula
    Wallace-Fitzsimons, Shauna E.
    Hyland, Niall
    Clarke, Gerard
    Dinan, Timothy G.
    [J]. PHYSIOLOGICAL REVIEWS, 2019, 99 (04) : 1877 - 2013
  • [2] Neuropeptides and the Microbiota-Gut-Brain Axis
    Holzer, Peter
    Farzi, Aitak
    [J]. MICROBIAL ENDOCRINOLOGY: THE MICROBIOTA-GUT-BRAIN AXIS IN HEALTH AND DISEASE, 2014, 817 : 195 - 219
  • [3] The microbiota-gut-brain axis in obesity
    Torres-Fuentes, Cristina
    Schellekens, Harriet
    Dinan, Timothy G.
    Cryan, John F.
    [J]. LANCET GASTROENTEROLOGY & HEPATOLOGY, 2017, 2 (10): : 747 - 756
  • [4] The Microbiota-Gut-Brain Axis and Epilepsy
    Yue, Qiang
    Cai, Mingfei
    Xiao, Bo
    Zhan, Qiong
    Zeng, Chang
    [J]. CELLULAR AND MOLECULAR NEUROBIOLOGY, 2022, 42 (02) : 439 - 453
  • [5] SnapShot: The microbiota-gut-brain axis
    Agirman, Gulistan
    Hsiao, Elaine Y.
    [J]. CELL, 2021, 184 (09) : 2524 - 2525
  • [6] Diet, Gut Physiology, and the Microbiota-Gut-Brain Axis
    Roy, N. C.
    [J]. PROCEEDINGS OF THE NUTRITION SOCIETY, 2024, 83 (OCE1)
  • [7] Gut feelings: the microbiota-gut-brain axis on steroids
    So, Sik Yu
    Savidge, Tor C.
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2022, 322 (01): : G1 - G20
  • [8] The Microbiota-Gut-Brain Axis and Diabetic Cognitive Impairment: A Memorable Journey
    Rai, Srinidhi
    Sreelatha, Souparnika
    Devang, Nayana
    Alva, Priya D.
    Raveendran, Arkiath Veettil
    [J]. CLINICAL DIABETOLOGY, 2023, 12 (04): : 261 - 271
  • [9] Dietary Influences on the Microbiota-Gut-Brain Axis
    Barber, Thomas M.
    Valsamakis, Georgios
    Mastorakos, George
    Hanson, Petra
    Kyrou, Ioannis
    Randeva, Harpal S.
    Weickert, Martin O.
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (07)
  • [10] The microbiota-gut-brain axis and neurodevelopmental disorders
    Wang, Qinwen
    Yang, Qianyue
    Liu, Xingyin
    [J]. PROTEIN & CELL, 2023, 14 (10) : 762 - 775
12345