Aldose reductase (AR) inhibitor (ARI) treatment stimulates AR gene transcription in glucose-exposed high AR-expressing human retinal pigment epithelial (RPE) cells

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作者：

Stevens, MJ

Larkin, D

Killen, PD

Greene, DA

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DIABETES | 1998年 / 47卷

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R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

246

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页码：A63 / A63

页数：1

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[1] Aldose reductase (AR) inhibition induces AR and taurine transporter gene transcription in glucose-exposed retinal figment epithelial (RPE) cells.
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[2] Glucose specific non-osmotic regulation of aldose reductase (AR) in human retinal pigment epithelial (RPE) cells in vitro
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[3] Overexpression of aldose reductase (AR) in human retinal pigment epithelial (RPE) cell lines is associated with a polymorphism in the AR basal promoter region
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[4] ALDOSE REDUCTASE (AR2) GENE-EXPRESSION IN CULTURED HUMAN RETINAL-PIGMENT EPITHELIAL-CELLS (RPE)
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[5] Non-osmotic induction of aldose reductase (AR) by pathophysiological levels of glucose in human retinal pigment epithelial cells (RPE) in vitro.
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[7] Cloning and characterization of the human taurine transporter promoter and transcriptional regulation-in low and high AR expressing retinal pigment epithelial (RPE) cells
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[8] Glucose-induced aldose reductase (AR) dependent suppression of Na-myo-inositol (MI) cotransporter (SMIT) gene expression and activity in human retinal pigment epithelial (RPE) cells is transcriptionally mediated
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[9] Effects of an aldose reductase inhibitor, fidarestat, on the increase of oxidative stress and VEGF production in human retinal pigment epithelial cells exposed to high glucose
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[10] GLUCOSE (G) POTENTIATION OR DEPRESSION OF BASAL AND CARBACHOL-(C)-STIMULATED PHOSPHOINOSITIDE (PI) AND DIACYLGLYCEROL (DAG) METABOLISM REFLECTS THE STATE OF ALDOSE REDUCTASE (AR) GENE-EXPRESSION IN RETINAL-PIGMENT EPITHELIAL (RPE) CELLS
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