Iodine Promoted Synthesis of Pyrano[3,2-c]quinoline-4,5-diones

被引：4
|
作者：
Zhou, Ting [1 ]
Wang, Daolin [1 ]
Qian, Jianhua [1 ]
Zhao, Wei [1 ]
机构：
[1] Bohai Univ, Coll Chem & Chem Engn, Key Lab Synth Applicat Funct Compound, Jinzhou 121003, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 37卷 / 06期
关键词：
quinoline; heterocycle; ultrasound irradiation; iodine; synthesis; CONSTITUENTS; ANTIFUNGAL; CYCLIZATION; PROGRESS;
D O I：
10.6023/cjoc201612001
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient method for the synthesis of pyrano[3,2-c]quinoline-4,5-dione derivatives via iodine promoted intramolecular cyclization of 1-methyl-3-cinnamoy1-4-hydroxyquinolin-2-one, synthesized from aldol condensation of 1-methyl-3-acetyl-4-hydroxyquinolin-2-one with aromatic aldehydes in the presence of pyridine and PEG-400 under ultrasound irradiation, has been described. This method offers the advantages of a green approach, easy work-up, mild conditions and good yields.
引用
收藏
页码：1548 / 1555
页数：8
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