Cervical Cancer Survivorship: Long-term Quality of Life and Social Support

被引:123
|
作者
Pfaendler, Krista S. [1 ]
Wenzel, Lari [2 ,3 ]
Mechanic, Mindy B. [4 ]
Penner, Kristine R.
机构
[1] Univ Calif Irvine, Dept Obstet & Gynecol, Div Gynecol Oncol, 101 City Dr S,Bldg 56,Suite 260, Orange, CA 92868 USA
[2] Univ Calif Irvine, Program Publ Hlth, Irvine, CA USA
[3] Univ Calif Irvine, Chao Family Comprehens Canc Ctr, Dept Med & Program Publ Hlth, Irvine, CA USA
[4] Calif State Univ Fullerton, Dept Psychol, Fullerton, CA 92634 USA
关键词
cervical cancer; long-term effects; quality of life; survivorship; CHAIN FATTY-ACIDS; RADICAL HYSTERECTOMY; RADIATION PROCTITIS; DOUBLE-BLIND; EARLY-STAGE; EUROPEAN-ORGANIZATION; EXTREMITY LYMPHEDEMA; URINARY-INCONTINENCE; LATE COMPLICATIONS; SEXUAL FUNCTION;
D O I
10.1016/j.clinthera.2014.11.013
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Purpose: Surgery, radiotherapy, and chemotherapy are the mainstays of cervical cancer treatment. Many patients receive multiple treatment modalities, each with its own long-term effects. Given the high 5-year survival rate for cervical cancer patients, evaluation and improvement of long-term quality of life are essential. Methods: Pertinent articles were identified through searches of Pub Med for literature published from 1993 to 2014. We summarize quality of life data from long-term follow-up studies of cervical cancer patients. We additionally summarize small group interviews of Hispanic and non-Hispanic cervical cancer survivors regarding social support and coping. Findings: Data are varied in terms of the long-term impact of treatment on quality of life, but consistent in suggesting that patients who receive radiotherapy as part of their treatment have the highest risk of increased long-term dysfunction of bladder and bowel, as well as sexual dysfunction and psychosocial consequences. Rigorous investigations regarding long-term consequences of treatment modalities are lacking. Implications: Continued work to improve treatment outcomes and survival should also include a focus on reducing adverse long-term side effects. Providing supportive care during treatment and evaluating the effects of supportive care can reduce the prevalence and magnitude of long-term sequelae of cervical cancer, which will in turn improve quality of life and quality of care. (C) 2015 Elsevier HS Journals, Inc. All rights reserved.
引用
收藏
页码:39 / 48
页数:10
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