Pharmacotherapies for Adolescent Substance Use Disorders

被引：10

作者：

Simkin, Deborah R. ^{[1
]}

Grenoble, Severin ^{[1
]}

机构：

[1] Univ S Alabama, Coll Med, Dept Psychiat, Div Child & Adolescent Psychiat, Mobile, AL USA

来源：

CHILD AND ADOLESCENT PSYCHIATRIC CLINICS OF NORTH AMERICA | 2010年 / 19卷 / 03期

关键词：

Adolescent; Substance use disorders; Pharmacotherapies; Developmental issues; Neurobiology; OPEN-LABEL TRIAL; MULTIMODAL INPATIENT PROGRAM; RANDOMIZED CONTROLLED-TRIAL; 12-MONTH ABSTINENCE RATES; PLACEBO-CONTROLLED TRIAL; COMMUNITY DRUG SERVICE; ALCOHOL-USE DISORDERS; DOUBLE-BLIND; COCAINE-DEPENDENCE; AVERSION THERAPY;

D O I：

10.1016/j.chc.2010.03.010

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

There is a paucity of research on pharmacotherapies in adolescents with substance use disorders. This paucity is partly because of the fact that most people with substance dependence do not get diagnosed until early adulthood, that is, after 18 years of age. This article reviews pharmacotherapies used for aversion, substitution, anti-craving, and detoxification of alcohol, nicotine, cocaine, and opioids dependence. Adult research is referenced when applicable and generalized to adolescents with caution. Continued evaluation and development of pharmacotherapy for youth in controlled studies are needed to examine medication effectiveness, safety, potential for abuse, compliance, and potential interactions with other medications or substances of abuse.

引用

页码：591 / +

页数：19

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