Primary therapy and survival among patients with nodular lymphocyte-predominant Hodgkin lymphoma: a population-based analysis in the Netherlands, 1993-2016

被引：13

作者：

Posthuma, Hidde L. A. ^{[1
]}

Zijlstra, Josee M. ^{[1
]}

Visser, Otto ^{[2
]}

Lugtenburg, Pieternella J. ^{[3
]}

Kersten, Marie Jose ^{[4
,5
]}

Dinmohamed, Avinash G. ^{[1
,4
,6
,7
]}

机构：

[1] Vrije Univ Amsterdam, Amsterdam UMC, Canc Ctr Amsterdam, Dept Haematol, Amsterdam, Netherlands

[2] Netherlands Comprehens Canc Org IKNL Utrecht, Dept Registrat, Utrecht, Netherlands

[3] Erasmus MC Canc Inst, Dept Haematol, Rotterdam, Netherlands

[4] Univ Amsterdam, Amsterdam UMC, Canc Ctr Amsterdam, Dept Haematol, Amsterdam, Netherlands

[5] Lymphoma & Myeloma Ctr Amsterdam LYMMCARE, Amsterdam, Netherlands

[6] Netherlands Comprehens Canc Org IKNL, Dept Res, Utrecht, Netherlands

[7] Erasmus MC, Dept Publ Hlth, Rotterdam, Netherlands

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2020年 / 189卷 / 01期

关键词：

nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL); cancer epidemiology; population-based registry; incidence; survival;

D O I：

10.1111/bjh.16290

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In this nationwide, population-based study, we assessed trends in primary treatment and survival among 687 patients with nodular lymphocyte-predominant Hodgkin lymphoma (75% males; median age, 40 years; and 74% stage-I/II disease) diagnosed in the Netherlands between 1993-2016. There were no noteworthy changes in the application of primary therapy over time among adult patients across the different disease stages and age groups. Survival among various subgroups of adult patients was largely comparable to the expected survival of the general population. A particularly encouraging finding was that young adult patients experienced virtually no excess mortality, as compared to the general population.

引用

页码：117 / 121

页数：5

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