Drug-eluting stents: caution and concerns for long-term outcome

被引：176
|
作者：
Virmani, R [1 ]
Farb, A [1 ]
Guagliumi, G [1 ]
Kolodgie, FD [1 ]
机构：
[1] Armed Forces Inst Pathol, Dept Cardiovasc Pathol, Washington, DC 20306 USA
来源：
CORONARY ARTERY DISEASE | 2004年 / 15卷 / 06期
关键词：
hypersensitivity; stents; thrombosis; sirolimus;
D O I：
10.1097/00019501-200409000-00003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Recent publications on drug-eluting stents (DES) report a significant reduction in restenosis rates as compared to bare metal stents in patients mostly with single vessel disease. We have recently observed however, late stent thrombosis following CYPHER(TM) DES implantation. The patient developed a hypersensitivity reaction around stent struts limited to the polymer with aneurysmal dilatation and extensive inflammation of the arterial wall in the absence of vascular healing. This incidence promotes a cautionary view and perhaps supports the use of DES only in high-risk patients. (C) 2004 Lippincott Williams Wilkins.
引用
收藏
页码：313 / 318
页数：6
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